rs17689531

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0071 (2132/29978,GnomAD)
C=0059 (1735/29118,TOPMED)
C=0043 (214/5008,1000G)
C=0098 (379/3854,ALSPAC)
C=0097 (361/3708,TWINSUK)
chr4:71157058 (GRCh38.p7) (4q13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
33 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.71157058T>C
GRCh37.p13 chr 4NC_000004.11:g.72022775T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.995C=0.005
1000GenomesAmericanSub694T=0.930C=0.070
1000GenomesEast AsianSub1008T=1.000C=0.000
1000GenomesEuropeSub1006T=0.886C=0.114
1000GenomesGlobalStudy-wide5008T=0.957C=0.043
1000GenomesSouth AsianSub978T=0.960C=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.902C=0.098
The Genome Aggregation DatabaseAfricanSub8736T=0.983C=0.017
The Genome Aggregation DatabaseAmericanSub838T=0.950C=0.050
The Genome Aggregation DatabaseEast AsianSub1610T=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18492T=0.898C=0.101
The Genome Aggregation DatabaseGlobalStudy-wide29978T=0.928C=0.071
The Genome Aggregation DatabaseOtherSub302T=0.800C=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.940C=0.059
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.903C=0.097
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs176895310.000786alcohol dependence21314694

eQTL of rs17689531 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17689531 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr47199736971997480E067-25295
chr47204988172050696E06727106
chr47205075172050806E06727976
chr47205157572051635E06728800
chr47199736971997480E068-25295
chr47199750671997788E068-24987
chr47199798671998185E068-24590
chr47199833471998476E068-24299
chr47204988172050696E06827106
chr47205157572051635E06928800
chr47199736971997480E070-25295
chr47199750671997788E070-24987
chr47199798671998185E070-24590
chr47199833471998476E070-24299
chr47199896671999220E070-23555
chr47199936671999467E070-23308
chr47205157572051635E07028800
chr47205157572051635E07128800
chr47206164672062046E07238871
chr47205157572051635E07428800
chr47199736971997480E081-25295
chr47199750671997788E081-24987
chr47199798671998185E081-24590
chr47199833471998476E081-24299
chr47206164672062046E08138871








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr47205170772054421E06728932
chr47205458772054716E06731812
chr47205474372054946E06731968
chr47199663171996893E068-25882
chr47199696771997234E068-25541
chr47205170772054421E06828932
chr47205458772054716E06831812
chr47205474372054946E06831968
chr47205532672055477E06832551
chr47199696771997234E069-25541
chr47205170772054421E06928932
chr47205170772054421E07028932
chr47205458772054716E07031812
chr47205474372054946E07031968
chr47205532672055477E07032551
chr47205170772054421E07128932
chr47205458772054716E07131812
chr47205474372054946E07131968
chr47205532672055477E07132551
chr47199663171996893E072-25882
chr47199696771997234E072-25541
chr47205170772054421E07228932
chr47205458772054716E07231812
chr47205474372054946E07231968
chr47205170772054421E07328932
chr47199663171996893E074-25882
chr47199696771997234E074-25541
chr47205170772054421E07428932
chr47205170772054421E08128932
chr47205458772054716E08131812
chr47205474372054946E08131968
chr47205532672055477E08132551
chr47205170772054421E08228932