rs17706299

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0036 (1078/29964,GnomAD)
G=0026 (775/29118,TOPMED)
G=0044 (222/5008,1000G)
G=0045 (173/3854,ALSPAC)
G=0047 (175/3708,TWINSUK)
chr11:109110090 (GRCh38.p7) (11q22.3)
ND
GWASdb2
1   publication(s)
See rs on genome
20 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.109110090C>G
GRCh37.p13 chr 11NC_000011.9:g.108980817C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.996G=0.004
1000GenomesAmericanSub694C=0.940G=0.060
1000GenomesEast AsianSub1008C=0.976G=0.024
1000GenomesEuropeSub1006C=0.957G=0.043
1000GenomesGlobalStudy-wide5008C=0.956G=0.044
1000GenomesSouth AsianSub978C=0.890G=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.955G=0.045
The Genome Aggregation DatabaseAfricanSub8732C=0.991G=0.009
The Genome Aggregation DatabaseAmericanSub838C=0.930G=0.070
The Genome Aggregation DatabaseEast AsianSub1618C=0.975G=0.025
The Genome Aggregation DatabaseEuropeSub18474C=0.952G=0.047
The Genome Aggregation DatabaseGlobalStudy-wide29964C=0.964G=0.036
The Genome Aggregation DatabaseOtherSub302C=0.930G=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.973G=0.026
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.953G=0.047
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs177062996.51E-05nicotine dependence17158188

eQTL of rs17706299 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17706299 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11108982801108984125E0701984
chr11108984207108984257E0703390
chr11108984380108984430E0703563
chr11108984586108984685E0703769
chr11108985289108985888E0704472
chr11108985982108986066E0705165
chr11108992332108992570E07011515
chr11109019535109019647E07438718
chr11109019677109019809E07438860
chr11108942088108942306E081-38511
chr11108942408108943081E081-37736
chr11108943156108943381E081-37436
chr11108982801108984125E0811984
chr11108984207108984257E0813390
chr11108984380108984430E0813563
chr11108984586108984685E0813769
chr11108982801108984125E0821984
chr11108984207108984257E0823390
chr11108984380108984430E0823563
chr11108984586108984685E0823769