rs17750015

Homo sapiens
T>C
WDR7 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0285 (8531/29938,GnomAD)
C=0261 (7625/29118,TOPMED)
C=0266 (1332/5008,1000G)
C=0373 (1439/3854,ALSPAC)
C=0363 (1345/3708,TWINSUK)
chr18:56730391 (GRCh38.p7) (18q21.31)
AD
GWASCatalog
1   publication(s)
See rs on genome
30 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.56730391T>C
GRCh37.p13 chr 18NC_000018.9:g.54397622T>C

Gene: WDR7, WD repeat domain 7(plus strand)

Molecule type Change Amino acid[Codon] SO Term
WDR7 transcript variant 1NM_015285.2:c.N/AIntron Variant
WDR7 transcript variant 2NM_052834.2:c.N/AIntron Variant
WDR7 transcript variant X1XM_006722431.2:c.N/AIntron Variant
WDR7 transcript variant X3XM_011525888.1:c.N/AIntron Variant
WDR7 transcript variant X2XM_017025682.1:c.N/AIntron Variant
WDR7 transcript variant X6XM_017025683.1:c.N/AIntron Variant
WDR7 transcript variant X4XR_001753170.1:n.N/AIntron Variant
WDR7 transcript variant X5XR_001753171.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.878C=0.122
1000GenomesAmericanSub694T=0.760C=0.240
1000GenomesEast AsianSub1008T=0.721C=0.279
1000GenomesEuropeSub1006T=0.608C=0.392
1000GenomesGlobalStudy-wide5008T=0.734C=0.266
1000GenomesSouth AsianSub978T=0.670C=0.330
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.627C=0.373
The Genome Aggregation DatabaseAfricanSub8726T=0.854C=0.146
The Genome Aggregation DatabaseAmericanSub836T=0.790C=0.210
The Genome Aggregation DatabaseEast AsianSub1616T=0.712C=0.288
The Genome Aggregation DatabaseEuropeSub18460T=0.648C=0.351
The Genome Aggregation DatabaseGlobalStudy-wide29938T=0.715C=0.285
The Genome Aggregation DatabaseOtherSub300T=0.590C=0.410
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.738C=0.261
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.637C=0.363
PMID Title Author Journal
22064162Genome-wide association study of comorbid depressive syndrome and alcohol dependence.Edwards ACPsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs177500158E-06alcohol dependence22064162

eQTL of rs17750015 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17750015 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr185434837254348422E067-49200
chr185442388954424241E06726267
chr185442424654424526E06726624
chr185434837254348422E068-49200
chr185434886254348926E068-48696
chr185440805254408113E06810430
chr185441160754411661E06813985
chr185441183954411893E06814217
chr185441198354412033E06814361
chr185441208154412131E06814459
chr185442388954424241E06826267
chr185442424654424526E06826624
chr185434837254348422E069-49200
chr185442424654424526E06926624
chr185444296154443011E06945339
chr185444303954443099E06945417
chr185444296154443011E07045339
chr185444303954443099E07045417
chr185444314154443223E07045519
chr185434837254348422E071-49200
chr185442424654424526E07126624
chr185443448254434532E07136860
chr185434837254348422E072-49200
chr185436427854364574E072-33048
chr185442388954424241E07226267
chr185442424654424526E07226624
chr185439398754394101E073-3521
chr185442388954424241E07426267
chr185442388954424241E08126267
chr185442424654424526E08126624