rs17753195

Homo sapiens
G>A
ADCK1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0059 (1789/29986,GnomAD)
A=0050 (1467/29118,TOPMED)
A=0045 (224/5008,1000G)
A=0077 (297/3854,ALSPAC)
A=0086 (320/3708,TWINSUK)
chr14:77885419 (GRCh38.p7) (14q24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
229 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.77885419G>A
GRCh37.p13 chr 14NC_000014.8:g.78351762G>A

Gene: ADCK1, aarF domain containing kinase 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ADCK1 transcript variant 2NM_001142545.1:c.N/AIntron Variant
ADCK1 transcript variant 1NM_020421.3:c.N/AIntron Variant
ADCK1 transcript variant X2XM_005267885.3:c.N/AIntron Variant
ADCK1 transcript variant X3XM_005267886.3:c.N/AIntron Variant
ADCK1 transcript variant X12XM_011536987.2:c.N/AIntron Variant
ADCK1 transcript variant X13XM_011536988.2:c.N/AIntron Variant
ADCK1 transcript variant X1XM_017021474.1:c.N/AIntron Variant
ADCK1 transcript variant X4XM_017021475.1:c.N/AIntron Variant
ADCK1 transcript variant X5XM_017021476.1:c.N/AIntron Variant
ADCK1 transcript variant X6XM_017021477.1:c.N/AIntron Variant
ADCK1 transcript variant X11XM_011536985.1:c.N/AGenic Upstream Transcript Variant
ADCK1 transcript variant X7XR_001750448.1:n.N/AIntron Variant
ADCK1 transcript variant X8XR_001750449.1:n.N/AIntron Variant
ADCK1 transcript variant X9XR_001750450.1:n.N/AIntron Variant
ADCK1 transcript variant X10XR_001750451.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.969A=0.031
1000GenomesAmericanSub694G=0.930A=0.070
1000GenomesEast AsianSub1008G=0.995A=0.005
1000GenomesEuropeSub1006G=0.907A=0.093
1000GenomesGlobalStudy-wide5008G=0.955A=0.045
1000GenomesSouth AsianSub978G=0.960A=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.923A=0.077
The Genome Aggregation DatabaseAfricanSub8736G=0.964A=0.036
The Genome Aggregation DatabaseAmericanSub838G=0.950A=0.050
The Genome Aggregation DatabaseEast AsianSub1622G=0.994A=0.006
The Genome Aggregation DatabaseEuropeSub18488G=0.924A=0.075
The Genome Aggregation DatabaseGlobalStudy-wide29986G=0.940A=0.059
The Genome Aggregation DatabaseOtherSub302G=0.900A=0.100
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.949A=0.050
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.914A=0.086
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs177531950.000514alcohol dependence21314694

eQTL of rs17753195 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17753195 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr147830476278304815E067-46947
chr147830515578306022E067-45740
chr147834495978345031E067-6731
chr147834507278345112E067-6650
chr147834525578345311E067-6451
chr147834541178345461E067-6301
chr147834555278345612E067-6150
chr147834561478345682E067-6080
chr147834576178345856E067-5906
chr147834841678348858E067-2904
chr147834896578349361E067-2401
chr147834936678349473E067-2289
chr147834952378349810E067-1952
chr147834992578350077E067-1685
chr147835015378350203E067-1559
chr147835020578350257E067-1505
chr147835038678350461E067-1301
chr147835064478350723E067-1039
chr147837619978376281E06724437
chr147837635378376537E06724591
chr147837668678376750E06724924
chr147837683978377029E06725077
chr147830476278304815E068-46947
chr147830515578306022E068-45740
chr147830952078310416E068-41346
chr147832715578327215E068-24547
chr147832747778327802E068-23960
chr147832781878327939E068-23823
chr147832824578328305E068-23457
chr147832833078328443E068-23319
chr147832850478329119E068-22643
chr147834749778347704E068-4058
chr147834791978348027E068-3735
chr147834841678348858E068-2904
chr147834896578349361E068-2401
chr147834936678349473E068-2289
chr147834952378349810E068-1952
chr147834992578350077E068-1685
chr147835015378350203E068-1559
chr147835020578350257E068-1505
chr147835038678350461E068-1301
chr147837582578375896E06824063
chr147837619978376281E06824437
chr147837635378376537E06824591
chr147837668678376750E06824924
chr147830407878304219E069-47543
chr147830446578304522E069-47240
chr147830476278304815E069-46947
chr147830515578306022E069-45740
chr147834495978345031E069-6731
chr147834507278345112E069-6650
chr147834525578345311E069-6451
chr147834541178345461E069-6301
chr147834555278345612E069-6150
chr147834561478345682E069-6080
chr147834576178345856E069-5906
chr147834592378346127E069-5635
chr147834841678348858E069-2904
chr147834896578349361E069-2401
chr147834936678349473E069-2289
chr147834952378349810E069-1952
chr147834992578350077E069-1685
chr147835015378350203E069-1559
chr147835020578350257E069-1505
chr147835038678350461E069-1301
chr147835064478350723E069-1039
chr147837582578375896E06924063
chr147837619978376281E06924437
chr147837635378376537E06924591
chr147837668678376750E06924924
chr147837683978377029E06925077
chr147837708378377190E06925321
chr147833480078334850E070-16912
chr147833518578335516E070-16246
chr147833563578335675E070-16087
chr147833571878335773E070-15989
chr147833941578339669E070-12093
chr147833970578339745E070-12017
chr147834525578345311E070-6451
chr147834541178345461E070-6301
chr147834555278345612E070-6150
chr147834561478345682E070-6080
chr147834576178345856E070-5906
chr147834592378346127E070-5635
chr147834632578346382E070-5380
chr147834643878346705E070-5057
chr147834700578347072E070-4690
chr147834707578347204E070-4558
chr147834729978347339E070-4423
chr147834737778347427E070-4335
chr147834749778347704E070-4058
chr147834791978348027E070-3735
chr147834841678348858E070-2904
chr147834896578349361E070-2401
chr147834936678349473E070-2289
chr147834952378349810E070-1952
chr147834992578350077E070-1685
chr147835015378350203E070-1559
chr147835020578350257E070-1505
chr147835038678350461E070-1301
chr147836872978368823E07016967
chr147836893378369016E07017171
chr147836931778369421E07017555
chr147838871478388758E07036952
chr147830407878304219E071-47543
chr147830446578304522E071-47240
chr147830476278304815E071-46947
chr147830952078310416E071-41346
chr147832747778327802E071-23960
chr147832781878327939E071-23823
chr147832824578328305E071-23457
chr147832833078328443E071-23319
chr147832850478329119E071-22643
chr147834525578345311E071-6451
chr147834541178345461E071-6301
chr147834555278345612E071-6150
chr147834561478345682E071-6080
chr147834576178345856E071-5906
chr147834841678348858E071-2904
chr147834896578349361E071-2401
chr147834936678349473E071-2289
chr147834952378349810E071-1952
chr147834992578350077E071-1685
chr147835015378350203E071-1559
chr147835020578350257E071-1505
chr147835038678350461E071-1301
chr147835064478350723E071-1039
chr147835184478351966E07182
chr147835208678352166E071324
chr147835228278352332E071520
chr147835242378352473E071661
chr147835250978352572E071747
chr147837582578375896E07124063
chr147837619978376281E07124437
chr147837635378376537E07124591
chr147837668678376750E07124924
chr147837683978377029E07125077
chr147838456978384660E07132807
chr147838469878384801E07132936
chr147838495878385095E07133196
chr147830407878304219E072-47543
chr147830446578304522E072-47240
chr147830476278304815E072-46947
chr147830515578306022E072-45740
chr147830952078310416E072-41346
chr147832824578328305E072-23457
chr147832833078328443E072-23319
chr147832850478329119E072-22643
chr147834495978345031E072-6731
chr147834507278345112E072-6650
chr147834525578345311E072-6451
chr147834541178345461E072-6301
chr147834555278345612E072-6150
chr147834561478345682E072-6080
chr147834576178345856E072-5906
chr147834841678348858E072-2904
chr147834896578349361E072-2401
chr147834936678349473E072-2289
chr147834952378349810E072-1952
chr147834992578350077E072-1685
chr147835015378350203E072-1559
chr147835020578350257E072-1505
chr147835038678350461E072-1301
chr147835064478350723E072-1039
chr147837582578375896E07224063
chr147837619978376281E07224437
chr147837635378376537E07224591
chr147837668678376750E07224924
chr147832747778327802E073-23960
chr147832824578328305E073-23457
chr147832833078328443E073-23319
chr147832850478329119E073-22643
chr147834841678348858E073-2904
chr147834896578349361E073-2401
chr147834936678349473E073-2289
chr147834952378349810E073-1952
chr147834992578350077E073-1685
chr147835015378350203E073-1559
chr147835020578350257E073-1505
chr147835038678350461E073-1301
chr147837619978376281E07324437
chr147837635378376537E07324591
chr147837668678376750E07324924
chr147837683978377029E07325077
chr147830407878304219E074-47543
chr147830446578304522E074-47240
chr147830476278304815E074-46947
chr147830515578306022E074-45740
chr147830952078310416E074-41346
chr147832824578328305E074-23457
chr147832833078328443E074-23319
chr147832850478329119E074-22643
chr147834495978345031E074-6731
chr147834507278345112E074-6650
chr147834525578345311E074-6451
chr147834541178345461E074-6301
chr147834555278345612E074-6150
chr147834561478345682E074-6080
chr147834576178345856E074-5906
chr147834592378346127E074-5635
chr147834841678348858E074-2904
chr147834896578349361E074-2401
chr147834936678349473E074-2289
chr147834952378349810E074-1952
chr147834992578350077E074-1685
chr147835015378350203E074-1559
chr147835020578350257E074-1505
chr147835038678350461E074-1301
chr147835064478350723E074-1039
chr147835082078350860E074-902
chr147835096378351013E074-749
chr147837582578375896E07424063
chr147837619978376281E07424437
chr147837635378376537E07424591
chr147837668678376750E07424924
chr147837683978377029E07425077
chr147837708378377190E07425321
chr147834896578349361E081-2401
chr147834936678349473E081-2289
chr147834952378349810E081-1952
chr147834992578350077E081-1685
chr147835015378350203E081-1559
chr147835020578350257E081-1505
chr147835038678350461E081-1301
chr147836931778369421E08117555
chr147836963778370030E08117875
chr147834841678348858E082-2904
chr147834896578349361E082-2401
chr147834936678349473E082-2289