rs1778369

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0231 (6896/29808,GnomAD)
T==0212 (1062/5008,1000G)
T==0282 (1088/3854,ALSPAC)
T==0283 (1048/3708,TWINSUK)
chr14:41299542 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41299542T>G
GRCh37.p13 chr 14NC_000014.8:g.41768745T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.126G=0.874
1000GenomesAmericanSub694T=0.210G=0.790
1000GenomesEast AsianSub1008T=0.167G=0.833
1000GenomesEuropeSub1006T=0.257G=0.743
1000GenomesGlobalStudy-wide5008T=0.212G=0.788
1000GenomesSouth AsianSub978T=0.330G=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.282G=0.718
The Genome Aggregation DatabaseAfricanSub8718T=0.183G=0.817
The Genome Aggregation DatabaseAmericanSub830T=0.170G=0.830
The Genome Aggregation DatabaseEast AsianSub1580T=0.195G=0.805
The Genome Aggregation DatabaseEuropeSub18378T=0.259G=0.740
The Genome Aggregation DatabaseGlobalStudy-wide29808T=0.231G=0.768
The Genome Aggregation DatabaseOtherSub302T=0.250G=0.750
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.283G=0.717
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17783690.000329nicotine dependence17158188

eQTL of rs1778369 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1778369 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144175450541754720E070-14025
chr144174720041747372E081-21373
chr144174720041747372E082-21373