SNP Detail Info-rs1778379

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0225 (6570/29118,TOPMED)
A==0242 (6365/26298,GnomAD)
A==0248 (1243/5008,1000G)
A==0283 (1089/3854,ALSPAC)
A==0278 (1030/3708,TWINSUK)

Position: chr14:41227751 (GRCh38.p7) (14q21.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.41227751A>G
GRCh37.p13 chr 14	NC_000014.8:g.41696954A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.148	G=0.852
1000Genomes	American	Sub	694	A=0.210	G=0.790
1000Genomes	East Asian	Sub	1008	A=0.303	G=0.697
1000Genomes	Europe	Sub	1006	A=0.263	G=0.737
1000Genomes	Global	Study-wide	5008	A=0.248	G=0.752
1000Genomes	South Asian	Sub	978	A=0.340	G=0.660
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.283	G=0.717
The Genome Aggregation Database	African	Sub	8050	A=0.187	G=0.813
The Genome Aggregation Database	American	Sub	628	A=0.170	G=0.830
The Genome Aggregation Database	East Asian	Sub	1568	A=0.301	G=0.699
The Genome Aggregation Database	Europe	Sub	15758	A=0.267	G=0.732
The Genome Aggregation Database	Global	Study-wide	26298	A=0.242	G=0.758
The Genome Aggregation Database	Other	Sub	294	A=0.240	G=0.760
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.225	G=0.774
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.278	G=0.722

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs1778379	0.000218	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs1778379