rs1778392

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0242 (7245/29900,GnomAD)
G==0225 (6573/29118,TOPMED)
G==0248 (1242/5008,1000G)
G==0284 (1093/3854,ALSPAC)
G==0279 (1035/3708,TWINSUK)
chr14:41246301 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41246301G>T
GRCh37.p13 chr 14NC_000014.8:g.41715504G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.148T=0.852
1000GenomesAmericanSub694G=0.210T=0.790
1000GenomesEast AsianSub1008G=0.303T=0.697
1000GenomesEuropeSub1006G=0.264T=0.736
1000GenomesGlobalStudy-wide5008G=0.248T=0.752
1000GenomesSouth AsianSub978G=0.340T=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.284T=0.716
The Genome Aggregation DatabaseAfricanSub8720G=0.187T=0.813
The Genome Aggregation DatabaseAmericanSub836G=0.170T=0.830
The Genome Aggregation DatabaseEast AsianSub1616G=0.304T=0.696
The Genome Aggregation DatabaseEuropeSub18426G=0.266T=0.733
The Genome Aggregation DatabaseGlobalStudy-wide29900G=0.242T=0.757
The Genome Aggregation DatabaseOtherSub302G=0.240T=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.225T=0.774
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.279T=0.721
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17783920.000141nicotine dependence17158188

eQTL of rs1778392 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1778392 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144175450541754720E07039001
chr144174720041747372E08131696
chr144174720041747372E08231696