SNP Detail Info-rs1778399

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0242 (7246/29926,GnomAD)
G==0226 (6580/29118,TOPMED)
G==0248 (1242/5008,1000G)
G==0284 (1093/3854,ALSPAC)
G==0279 (1036/3708,TWINSUK)

Position: chr14:41250163 (GRCh38.p7) (14q21.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.41250163G>A
GRCh37.p13 chr 14	NC_000014.8:g.41719366G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.148	A=0.852
1000Genomes	American	Sub	694	G=0.210	A=0.790
1000Genomes	East Asian	Sub	1008	G=0.303	A=0.697
1000Genomes	Europe	Sub	1006	G=0.264	A=0.736
1000Genomes	Global	Study-wide	5008	G=0.248	A=0.752
1000Genomes	South Asian	Sub	978	G=0.340	A=0.660
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.284	A=0.716
The Genome Aggregation Database	African	Sub	8710	G=0.186	A=0.814
The Genome Aggregation Database	American	Sub	836	G=0.170	A=0.830
The Genome Aggregation Database	East Asian	Sub	1614	G=0.304	A=0.696
The Genome Aggregation Database	Europe	Sub	18466	G=0.266	A=0.733
The Genome Aggregation Database	Global	Study-wide	29926	G=0.242	A=0.757
The Genome Aggregation Database	Other	Sub	300	G=0.240	A=0.760
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.226	A=0.774
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.279	A=0.721

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs1778399	0.000169	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr14	41754505	41754720	E070	35139
chr14	41747200	41747372	E081	27834
chr14	41747200	41747372	E082	27834

rs1778399