SNP Detail Info-rs1778401

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0241 (7241/29930,GnomAD)
A==0225 (6577/29118,TOPMED)
A==0247 (1237/5008,1000G)
A==0284 (1093/3854,ALSPAC)
A==0279 (1035/3708,TWINSUK)

Position: chr14:41252558 (GRCh38.p7) (14q21.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.41252558A>G
GRCh37.p13 chr 14	NC_000014.8:g.41721761A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.148	G=0.852
1000Genomes	American	Sub	694	A=0.210	G=0.790
1000Genomes	East Asian	Sub	1008	A=0.298	G=0.702
1000Genomes	Europe	Sub	1006	A=0.264	G=0.736
1000Genomes	Global	Study-wide	5008	A=0.247	G=0.753
1000Genomes	South Asian	Sub	978	A=0.340	G=0.660
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.284	G=0.716
The Genome Aggregation Database	African	Sub	8722	A=0.187	G=0.813
The Genome Aggregation Database	American	Sub	836	A=0.170	G=0.830
The Genome Aggregation Database	East Asian	Sub	1616	A=0.300	G=0.700
The Genome Aggregation Database	Europe	Sub	18454	A=0.266	G=0.734
The Genome Aggregation Database	Global	Study-wide	29930	A=0.241	G=0.758
The Genome Aggregation Database	Other	Sub	302	A=0.240	G=0.760
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.225	G=0.774
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.279	G=0.721

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs1778401	0.000129	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr14	41754505	41754720	E070	32744
chr14	41747200	41747372	E081	25439
chr14	41747200	41747372	E082	25439

rs1778401