rs1779521

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0242 (7242/29918,GnomAD)
T==0225 (6579/29118,TOPMED)
T==0247 (1237/5008,1000G)
T==0284 (1093/3854,ALSPAC)
T==0279 (1035/3708,TWINSUK)
chr14:41251855 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41251855T>C
GRCh37.p13 chr 14NC_000014.8:g.41721058T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.148C=0.852
1000GenomesAmericanSub694T=0.210C=0.790
1000GenomesEast AsianSub1008T=0.298C=0.702
1000GenomesEuropeSub1006T=0.264C=0.736
1000GenomesGlobalStudy-wide5008T=0.247C=0.753
1000GenomesSouth AsianSub978T=0.340C=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.284C=0.716
The Genome Aggregation DatabaseAfricanSub8702T=0.186C=0.814
The Genome Aggregation DatabaseAmericanSub838T=0.170C=0.830
The Genome Aggregation DatabaseEast AsianSub1614T=0.300C=0.700
The Genome Aggregation DatabaseEuropeSub18462T=0.266C=0.733
The Genome Aggregation DatabaseGlobalStudy-wide29918T=0.242C=0.757
The Genome Aggregation DatabaseOtherSub302T=0.240C=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.225C=0.774
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.279C=0.721
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17795210.000127nicotine dependence17158188

eQTL of rs1779521 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1779521 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144175450541754720E07033447
chr144174720041747372E08126142
chr144174720041747372E08226142