rs1779530

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0242 (7246/29924,GnomAD)
C==0226 (6586/29118,TOPMED)
C==0248 (1243/5008,1000G)
C==0283 (1091/3854,ALSPAC)
C==0279 (1034/3708,TWINSUK)
chr14:41232115 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41232115C>T
GRCh37.p13 chr 14NC_000014.8:g.41701318C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.148T=0.852
1000GenomesAmericanSub694C=0.210T=0.790
1000GenomesEast AsianSub1008C=0.303T=0.697
1000GenomesEuropeSub1006C=0.264T=0.736
1000GenomesGlobalStudy-wide5008C=0.248T=0.752
1000GenomesSouth AsianSub978C=0.340T=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.283T=0.717
The Genome Aggregation DatabaseAfricanSub8720C=0.187T=0.813
The Genome Aggregation DatabaseAmericanSub834C=0.170T=0.830
The Genome Aggregation DatabaseEast AsianSub1616C=0.303T=0.697
The Genome Aggregation DatabaseEuropeSub18452C=0.265T=0.734
The Genome Aggregation DatabaseGlobalStudy-wide29924C=0.242T=0.757
The Genome Aggregation DatabaseOtherSub302C=0.240T=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.226T=0.773
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.279T=0.721
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17795300.000201nicotine dependence17158188

eQTL of rs1779530 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1779530 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144174720041747372E08145882
chr144174720041747372E08245882