rs1779534

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0248 (7447/29920,GnomAD)
T==0234 (6829/29118,TOPMED)
T==0258 (1293/5008,1000G)
T==0284 (1093/3854,ALSPAC)
T==0279 (1035/3708,TWINSUK)
chr14:41230201 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41230201T>C
GRCh37.p13 chr 14NC_000014.8:g.41699404T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.186C=0.814
1000GenomesAmericanSub694T=0.210C=0.790
1000GenomesEast AsianSub1008T=0.303C=0.697
1000GenomesEuropeSub1006T=0.263C=0.737
1000GenomesGlobalStudy-wide5008T=0.258C=0.742
1000GenomesSouth AsianSub978T=0.340C=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.284C=0.716
The Genome Aggregation DatabaseAfricanSub8710T=0.210C=0.790
The Genome Aggregation DatabaseAmericanSub836T=0.170C=0.830
The Genome Aggregation DatabaseEast AsianSub1614T=0.304C=0.696
The Genome Aggregation DatabaseEuropeSub18458T=0.266C=0.733
The Genome Aggregation DatabaseGlobalStudy-wide29920T=0.248C=0.751
The Genome Aggregation DatabaseOtherSub302T=0.240C=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.234C=0.765
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.279C=0.721
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17795340.000131nicotine dependence17158188

eQTL of rs1779534 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1779534 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144174720041747372E08147796
chr144174720041747372E08247796