rs1782135

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0242 (7238/29894,GnomAD)
A==0226 (6580/29118,TOPMED)
A==0247 (1237/5008,1000G)
A==0283 (1091/3854,ALSPAC)
A==0279 (1034/3708,TWINSUK)
chr14:41246797 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41246797A>G
GRCh37.p13 chr 14NC_000014.8:g.41716000A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.148G=0.852
1000GenomesAmericanSub694A=0.210G=0.790
1000GenomesEast AsianSub1008A=0.298G=0.702
1000GenomesEuropeSub1006A=0.264G=0.736
1000GenomesGlobalStudy-wide5008A=0.247G=0.753
1000GenomesSouth AsianSub978A=0.340G=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.283G=0.717
The Genome Aggregation DatabaseAfricanSub8714A=0.187G=0.813
The Genome Aggregation DatabaseAmericanSub836A=0.170G=0.830
The Genome Aggregation DatabaseEast AsianSub1610A=0.301G=0.699
The Genome Aggregation DatabaseEuropeSub18432A=0.266G=0.733
The Genome Aggregation DatabaseGlobalStudy-wide29894A=0.242G=0.757
The Genome Aggregation DatabaseOtherSub302A=0.240G=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.226G=0.774
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.279G=0.721
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17821350.000205nicotine dependence17158188

eQTL of rs1782135 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1782135 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144175450541754720E07038505
chr144174720041747372E08131200
chr144174720041747372E08231200