SNP Detail Info-rs1782139

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0242 (7253/29920,GnomAD)
A==0225 (6579/29118,TOPMED)
A==0247 (1236/5008,1000G)
A==0284 (1093/3854,ALSPAC)
A==0279 (1036/3708,TWINSUK)

Position: chr14:41254382 (GRCh38.p7) (14q21.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.41254382A>G
GRCh37.p13 chr 14	NC_000014.8:g.41723585A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.148	G=0.852
1000Genomes	American	Sub	694	A=0.210	G=0.790
1000Genomes	East Asian	Sub	1008	A=0.298	G=0.702
1000Genomes	Europe	Sub	1006	A=0.263	G=0.737
1000Genomes	Global	Study-wide	5008	A=0.247	G=0.753
1000Genomes	South Asian	Sub	978	A=0.340	G=0.660
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.284	G=0.716
The Genome Aggregation Database	African	Sub	8704	A=0.187	G=0.813
The Genome Aggregation Database	American	Sub	832	A=0.180	G=0.820
The Genome Aggregation Database	East Asian	Sub	1618	A=0.303	G=0.697
The Genome Aggregation Database	Europe	Sub	18464	A=0.266	G=0.733
The Genome Aggregation Database	Global	Study-wide	29920	A=0.242	G=0.757
The Genome Aggregation Database	Other	Sub	302	A=0.240	G=0.760
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.225	G=0.774
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.279	G=0.721

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs1782139	0.000106	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr14	41754505	41754720	E070	30920
chr14	41747200	41747372	E081	23615
chr14	41747200	41747372	E082	23615

rs1782139