SNP Detail Info-rs1782144

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0249 (7474/29912,GnomAD)
G==0235 (6869/29118,TOPMED)
G==0256 (1283/5008,1000G)
G==0280 (1079/3854,ALSPAC)
G==0277 (1027/3708,TWINSUK)

Position: chr14:41260570 (GRCh38.p7) (14q21.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.41260570G>A
GRCh37.p13 chr 14	NC_000014.8:g.41729773G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.185	A=0.815
1000Genomes	American	Sub	694	G=0.210	A=0.790
1000Genomes	East Asian	Sub	1008	G=0.297	A=0.703
1000Genomes	Europe	Sub	1006	G=0.264	A=0.736
1000Genomes	Global	Study-wide	5008	G=0.256	A=0.744
1000Genomes	South Asian	Sub	978	G=0.330	A=0.670
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.280	A=0.720
The Genome Aggregation Database	African	Sub	8700	G=0.215	A=0.785
The Genome Aggregation Database	American	Sub	836	G=0.180	A=0.820
The Genome Aggregation Database	East Asian	Sub	1606	G=0.303	A=0.697
The Genome Aggregation Database	Europe	Sub	18468	G=0.265	A=0.734
The Genome Aggregation Database	Global	Study-wide	29912	G=0.249	A=0.750
The Genome Aggregation Database	Other	Sub	302	G=0.240	A=0.760
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.235	A=0.764
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.277	A=0.723

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs1782144	9.88E-05	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr14	41754505	41754720	E070	24732
chr14	41747200	41747372	E081	17427
chr14	41747200	41747372	E082	17427

rs1782144