rs1782159

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0238 (7130/29882,GnomAD)
C==0220 (6423/29118,TOPMED)
C==0230 (1154/5008,1000G)
C==0283 (1091/3854,ALSPAC)
C==0283 (1049/3708,TWINSUK)
chr14:41287366 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41287366C>T
GRCh37.p13 chr 14NC_000014.8:g.41756569C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.126T=0.874
1000GenomesAmericanSub694C=0.210T=0.790
1000GenomesEast AsianSub1008C=0.250T=0.750
1000GenomesEuropeSub1006C=0.263T=0.737
1000GenomesGlobalStudy-wide5008C=0.230T=0.770
1000GenomesSouth AsianSub978C=0.330T=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.283T=0.717
The Genome Aggregation DatabaseAfricanSub8708C=0.183T=0.817
The Genome Aggregation DatabaseAmericanSub834C=0.170T=0.830
The Genome Aggregation DatabaseEast AsianSub1584C=0.261T=0.739
The Genome Aggregation DatabaseEuropeSub18456C=0.266T=0.734
The Genome Aggregation DatabaseGlobalStudy-wide29882C=0.238T=0.761
The Genome Aggregation DatabaseOtherSub300C=0.240T=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.220T=0.779
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.283T=0.717
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17821591.87E-05nicotine dependence17158188

eQTL of rs1782159 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1782159 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144175450541754720E070-1849
chr144174720041747372E081-9197
chr144174720041747372E082-9197