rs1782163

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0229 (6838/29832,GnomAD)
C==0217 (6321/29118,TOPMED)
C==0209 (1049/5008,1000G)
C==0282 (1088/3854,ALSPAC)
C==0282 (1047/3708,TWINSUK)
chr14:41296726 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41296726C>T
GRCh37.p13 chr 14NC_000014.8:g.41765929C>T
LOC100533628 pseudogeneNG_028872.1:g.417C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.119T=0.881
1000GenomesAmericanSub694C=0.210T=0.790
1000GenomesEast AsianSub1008C=0.166T=0.834
1000GenomesEuropeSub1006C=0.257T=0.743
1000GenomesGlobalStudy-wide5008C=0.209T=0.791
1000GenomesSouth AsianSub978C=0.330T=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.282T=0.718
The Genome Aggregation DatabaseAfricanSub8708C=0.176T=0.824
The Genome Aggregation DatabaseAmericanSub830C=0.170T=0.830
The Genome Aggregation DatabaseEast AsianSub1578C=0.196T=0.804
The Genome Aggregation DatabaseEuropeSub18414C=0.259T=0.740
The Genome Aggregation DatabaseGlobalStudy-wide29832C=0.229T=0.770
The Genome Aggregation DatabaseOtherSub302C=0.250T=0.750
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.217T=0.782
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.282T=0.718
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17821630.000377nicotine dependence17158188

eQTL of rs1782163 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1782163 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144175450541754720E070-11209
chr144174720041747372E081-18557
chr144174720041747372E082-18557