rs1782180

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
C==0248 (7442/29914,GnomAD)
C==0234 (6838/29118,TOPMED)
C==0257 (1289/5008,1000G)
C==0284 (1094/3854,ALSPAC)
C==0279 (1034/3708,TWINSUK)
chr14:41227362 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41227362C>A
GRCh37.p13 chr 14NC_000014.8:g.41696565C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.182A=0.818
1000GenomesAmericanSub694C=0.220A=0.780
1000GenomesEast AsianSub1008C=0.303A=0.697
1000GenomesEuropeSub1006C=0.263A=0.737
1000GenomesGlobalStudy-wide5008C=0.257A=0.743
1000GenomesSouth AsianSub978C=0.340A=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.284A=0.716
The Genome Aggregation DatabaseAfricanSub8714C=0.210A=0.790
The Genome Aggregation DatabaseAmericanSub834C=0.170A=0.830
The Genome Aggregation DatabaseEast AsianSub1616C=0.303A=0.697
The Genome Aggregation DatabaseEuropeSub18448C=0.266A=0.734
The Genome Aggregation DatabaseGlobalStudy-wide29914C=0.248A=0.751
The Genome Aggregation DatabaseOtherSub302C=0.240A=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.234A=0.765
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.279A=0.721
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17821800.000174nicotine dependence17158188

eQTL of rs1782180 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1782180 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.