rs1787984

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0407 (12155/29842,GnomAD)
G=0481 (14025/29118,TOPMED)
G=0471 (2357/5008,1000G)
G=0270 (1042/3854,ALSPAC)
G=0263 (977/3708,TWINSUK)
chr18:11972440 (GRCh38.p7) (18p11.21)
AD
GWASdb2
2   publication(s)
See rs on genome
88 Enhancers around
15 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.11972440A>G
GRCh37.p13 chr 18NC_000018.9:g.11972439A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.195G=0.805
1000GenomesAmericanSub694A=0.730G=0.270
1000GenomesEast AsianSub1008A=0.565G=0.435
1000GenomesEuropeSub1006A=0.773G=0.227
1000GenomesGlobalStudy-wide5008A=0.529G=0.471
1000GenomesSouth AsianSub978A=0.550G=0.450
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.730G=0.270
The Genome Aggregation DatabaseAfricanSub8704A=0.281G=0.719
The Genome Aggregation DatabaseAmericanSub836A=0.730G=0.270
The Genome Aggregation DatabaseEast AsianSub1608A=0.614G=0.386
The Genome Aggregation DatabaseEuropeSub18394A=0.729G=0.270
The Genome Aggregation DatabaseGlobalStudy-wide29842A=0.592G=0.407
The Genome Aggregation DatabaseOtherSub300A=0.760G=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.518G=0.481
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.737G=0.263
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
20800640Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder.Bloch PJProg Neuropsychopharmacol Biol Psychiatry

P-Value

SNP ID p-value Traits Study
rs17879840.00021alcohol dependence20201924

eQTL of rs1787984 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1787984 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr181196275411962961E067-9478
chr181196306811963176E067-9263
chr181199417211996346E06721733
chr181201513512016128E06742696
chr181201614812016320E06743709
chr181195434411954832E068-17607
chr181195485311955116E068-17323
chr181195517011955236E068-17203
chr181195526511956010E068-16429
chr181199417211996346E06821733
chr181201513512016128E06842696
chr181201614812016320E06843709
chr181201438012014434E06941941
chr181201448112014531E06942042
chr181201467012014714E06942231
chr181201478612014951E06942347
chr181201513512016128E06942696
chr181201614812016320E06943709
chr181195485311955116E070-17323
chr181195517011955236E070-17203
chr181195526511956010E070-16429
chr181198686311986913E07014424
chr181199700711997225E07024568
chr181199732011997389E07024881
chr181199768111997764E07025242
chr181199781511997880E07025376
chr181199796311998007E07025524
chr181199811311998163E07025674
chr181199824311998534E07025804
chr181199861711998676E07026178
chr181199953911999650E07027100
chr181199978111999835E07027342
chr181201243212012725E07039993
chr181201274012013145E07040301
chr181201322712013594E07040788
chr181201375312013854E07041314
chr181201501112015102E07042572
chr181201513512016128E07042696
chr181201614812016320E07043709
chr181195434411954832E071-17607
chr181195485311955116E071-17323
chr181195517011955236E071-17203
chr181195526511956010E071-16429
chr181196275411962961E071-9478
chr181196306811963176E071-9263
chr181199417211996346E07121733
chr181199635311996452E07123914
chr181199655611996606E07124117
chr181199662611996775E07124187
chr181199686111996981E07124422
chr181199700711997225E07124568
chr181199732011997389E07124881
chr181199768111997764E07125242
chr181199781511997880E07125376
chr181199796311998007E07125524
chr181199811311998163E07125674
chr181199824311998534E07125804
chr181201513512016128E07142696
chr181199417211996346E07221733
chr181201513512016128E07242696
chr181201614812016320E07243709
chr181199417211996346E07321733
chr181201274012013145E07340301
chr181201322712013594E07340788
chr181201513512016128E07342696
chr181195526511956010E074-16429
chr181201501112015102E07442572
chr181201513512016128E07442696
chr181201614812016320E07443709
chr181201375312013854E08141314
chr181201418012014224E08141741
chr181201425712014376E08141818
chr181201438012014434E08141941
chr181201448112014531E08142042
chr181201467012014714E08142231
chr181201478612014951E08142347
chr181201501112015102E08142572
chr181201513512016128E08142696
chr181199905211999127E08226613
chr181199953911999650E08227100
chr181199978111999835E08227342
chr181201438012014434E08241941
chr181201448112014531E08242042
chr181201467012014714E08242231
chr181201478612014951E08242347
chr181201501112015102E08242572
chr181201513512016128E08242696
chr181201614812016320E08243709










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr181194605311948381E067-24058
chr181197988711982541E0677448
chr181194605311948381E068-24058
chr181197988711982541E0687448
chr181194605311948381E069-24058
chr181197988711982541E0697448
chr181197988711982541E0707448
chr181194605311948381E071-24058
chr181197988711982541E0717448
chr181197988711982541E0727448
chr181194605311948381E073-24058
chr181197988711982541E0737448
chr181194605311948381E074-24058
chr181197988711982541E0747448
chr181197988711982541E0827448