rs1791124

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0198 (5951/29936,GnomAD)
G=0244 (7125/29118,TOPMED)
G=0213 (1065/5008,1000G)
G=0116 (448/3854,ALSPAC)
G=0124 (460/3708,TWINSUK)
chr18:3316178 (GRCh38.p7) (18p11.31)
AD
GWASdb2
1   publication(s)
See rs on genome
100 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.3316178T>G
GRCh37.p13 chr 18NC_000018.9:g.3316176T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.638G=0.362
1000GenomesAmericanSub694T=0.780G=0.220
1000GenomesEast AsianSub1008T=0.840G=0.160
1000GenomesEuropeSub1006T=0.863G=0.137
1000GenomesGlobalStudy-wide5008T=0.787G=0.213
1000GenomesSouth AsianSub978T=0.860G=0.140
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.884G=0.116
The Genome Aggregation DatabaseAfricanSub8700T=0.658G=0.342
The Genome Aggregation DatabaseAmericanSub832T=0.700G=0.300
The Genome Aggregation DatabaseEast AsianSub1616T=0.830G=0.170
The Genome Aggregation DatabaseEuropeSub18486T=0.869G=0.130
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.801G=0.198
The Genome Aggregation DatabaseOtherSub302T=0.850G=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.755G=0.244
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.876G=0.124
PMID Title Author Journal
19581569Genome-wide association study of alcohol dependence.Treutlein JArch Gen Psychiatry

P-Value

SNP ID p-value Traits Study
rs17911241.85E-05alcohol dependence19581569

eQTL of rs1791124 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1791124 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1832667393266819E067-49357
chr1832668403266894E067-49282
chr1832669083267029E067-49147
chr1832670883267311E067-48865
chr1832673513267475E067-48701
chr1832832873284315E067-31861
chr1833587983358916E06742622
chr1833592013359370E06743025
chr1833596493359729E06743473
chr1833597713359865E06743595
chr1833599093360039E06743733
chr1833602793360774E06744103
chr1832667393266819E068-49357
chr1832668403266894E068-49282
chr1832669083267029E068-49147
chr1832670883267311E068-48865
chr1832673513267475E068-48701
chr1832677993267853E068-48323
chr1832681653268270E068-47906
chr1832691993269819E068-46357
chr1832701023270179E068-45997
chr1832843933284444E068-31732
chr1833596493359729E06843473
chr1833597713359865E06843595
chr1833599093360039E06843733
chr1833602793360774E06844103
chr1833608813361067E06844705
chr1833610813361161E06844905
chr1833611943361293E06845018
chr1833613343361478E06845158
chr1833615323361704E06845356
chr1833617153361827E06845539
chr1832667393266819E069-49357
chr1832668403266894E069-49282
chr1832669083267029E069-49147
chr1832670883267311E069-48865
chr1832691993269819E069-46357
chr1833592013359370E06943025
chr1833596493359729E06943473
chr1833597713359865E06943595
chr1833599093360039E06943733
chr1833602793360774E06944103
chr1833613343361478E06945158
chr1832832873284315E070-31861
chr1833293293330374E07013153
chr1833478413348028E07031665
chr1832667393266819E071-49357
chr1832668403266894E071-49282
chr1832669083267029E071-49147
chr1832670883267311E071-48865
chr1832673513267475E071-48701
chr1832681653268270E071-47906
chr1832683673268670E071-47506
chr1832687773269163E071-47013
chr1832691993269819E071-46357
chr1832701023270179E071-45997
chr1832704233270578E071-45598
chr1832813763282357E071-33819
chr1832843933284444E071-31732
chr1833592013359370E07143025
chr1833596493359729E07143473
chr1833597713359865E07143595
chr1833599093360039E07143733
chr1832683673268670E072-47506
chr1832687773269163E072-47013
chr1832691993269819E072-46357
chr1832704233270578E072-45598
chr1832832873284315E072-31861
chr1832843933284444E072-31732
chr1832846443284787E072-31389
chr1833592013359370E07243025
chr1833596493359729E07243473
chr1833597713359865E07243595
chr1833599093360039E07243733
chr1833602793360774E07244103
chr1833608813361067E07244705
chr1833615323361704E07245356
chr1832691993269819E073-46357
chr1832832873284315E073-31861
chr1832843933284444E073-31732
chr1832846443284787E073-31389
chr1832667393266819E074-49357
chr1832691993269819E074-46357
chr1832701023270179E074-45997
chr1832813763282357E074-33819
chr1832825573283206E074-32970
chr1832832873284315E074-31861
chr1832843933284444E074-31732
chr1833587983358916E07442622
chr1833592013359370E07443025
chr1833596493359729E07443473
chr1833597713359865E07443595
chr1833599093360039E07443733
chr1833602793360774E07444103
chr1833615323361704E07445356
chr1832832873284315E081-31861
chr1832843933284444E081-31732
chr1833284293329260E08112253
chr1833293293330374E08113153
chr1833284293329260E08212253










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1832967723297825E067-18351
chr1832967723297825E068-18351
chr1832967723297825E069-18351
chr1832967723297825E070-18351
chr1832967723297825E071-18351
chr1832967723297825E072-18351
chr1832967723297825E073-18351
chr1832967723297825E074-18351
chr1832967723297825E082-18351