rs179661

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0212 (6370/29944,GnomAD)
A=0231 (6732/29118,TOPMED)
A=0266 (1333/5008,1000G)
A=0188 (724/3854,ALSPAC)
A=0204 (755/3708,TWINSUK)
chr14:30859665 (GRCh38.p7) (14q12)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
12 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.30859665G>A
GRCh37.p13 chr 14NC_000014.8:g.31328871G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.766A=0.234
1000GenomesAmericanSub694G=0.650A=0.350
1000GenomesEast AsianSub1008G=0.693A=0.307
1000GenomesEuropeSub1006G=0.801A=0.199
1000GenomesGlobalStudy-wide5008G=0.734A=0.266
1000GenomesSouth AsianSub978G=0.720A=0.280
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.812A=0.188
The Genome Aggregation DatabaseAfricanSub8714G=0.750A=0.250
The Genome Aggregation DatabaseAmericanSub838G=0.680A=0.320
The Genome Aggregation DatabaseEast AsianSub1612G=0.743A=0.257
The Genome Aggregation DatabaseEuropeSub18478G=0.814A=0.185
The Genome Aggregation DatabaseGlobalStudy-wide29944G=0.787A=0.212
The Genome Aggregation DatabaseOtherSub302G=0.710A=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.768A=0.231
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.796A=0.204
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs1796610.000254alcohol consumption (maxi-drinks)24277619

eQTL of rs179661 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs179661 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr143134294731345287E06714076
chr143134294731345287E06814076
chr143134568631345736E06816815
chr143134592131345971E06817050
chr143134759931347649E06818728
chr143134294731345287E06914076
chr143134294731345287E07014076
chr143134294731345287E07114076
chr143134294731345287E07214076
chr143134294731345287E07314076
chr143134294731345287E07414076
chr143134294731345287E08214076