rs1806590

Homo sapiens
A>G / A>T
GRID1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0335 (10009/29816,GnomAD)
G=0363 (10573/29118,TOPMED)
G=0365 (1828/5008,1000G)
G=0226 (871/3854,ALSPAC)
G=0218 (810/3708,TWINSUK)
chr10:86086042 (GRCh38.p7) (10q23.1)
ND
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.86086042A>G
GRCh38.p7 chr 10NC_000010.11:g.86086042A>T
GRCh37.p13 chr 10NC_000010.10:g.87845799A>G
GRCh37.p13 chr 10NC_000010.10:g.87845799A>T
GRID1 RefSeqGeneNG_011875.1:g.285452T>C
GRID1 RefSeqGeneNG_011875.1:g.285452T>A

Gene: GRID1, glutamate ionotropic receptor delta type subunit 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
GRID1 transcriptNM_017551.2:c.N/AIntron Variant
GRID1 transcript variant X1XM_011539720.2:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.387G=0.613
1000GenomesAmericanSub694A=0.750G=0.250
1000GenomesEast AsianSub1008A=0.749G=0.251
1000GenomesEuropeSub1006A=0.756G=0.244
1000GenomesGlobalStudy-wide5008A=0.635G=0.365
1000GenomesSouth AsianSub978A=0.640G=0.360
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.774G=0.226
The Genome Aggregation DatabaseAfricanSub8674A=0.442T=0.000
The Genome Aggregation DatabaseAmericanSub836A=0.720T=0.00,
The Genome Aggregation DatabaseEast AsianSub1612A=0.788T=0.000
The Genome Aggregation DatabaseEuropeSub18392A=0.754T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29816A=0.664T=0.000
The Genome Aggregation DatabaseOtherSub302A=0.750T=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.636G=0.363
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.782G=0.218
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs18065900.000243nicotine dependence17158188

eQTL of rs1806590 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1806590 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr104508270145082784E07028521
chr104508531745085485E07031137