rs183008

Homo sapiens
T>C
SNX29 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0352 (10510/29830,GnomAD)
T==0325 (9482/29118,TOPMED)
T==0277 (1387/5008,1000G)
T==0418 (1611/3854,ALSPAC)
T==0411 (1524/3708,TWINSUK)
chr16:12107834 (GRCh38.p7) (16p13.13)
AD
GWASdb2
1   publication(s)
See rs on genome
190 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.12107834T>C
GRCh37.p13 chr 16NC_000016.9:g.12201691T>C

Gene: SNX29, sorting nexin 29(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SNX29 transcriptNM_032167.4:c.N/AIntron Variant
SNX29 transcript variant X9XM_005255682.3:c.N/AIntron Variant
SNX29 transcript variant X12XM_005255683.3:c.N/AIntron Variant
SNX29 transcript variant X1XM_011522738.2:c.N/AIntron Variant
SNX29 transcript variant X5XM_011522741.2:c.N/AIntron Variant
SNX29 transcript variant X7XM_011522743.2:c.N/AIntron Variant
SNX29 transcript variant X10XM_011522744.2:c.N/AIntron Variant
SNX29 transcript variant X3XM_017023871.1:c.N/AIntron Variant
SNX29 transcript variant X4XM_017023872.1:c.N/AIntron Variant
SNX29 transcript variant X6XM_017023873.1:c.N/AIntron Variant
SNX29 transcript variant X8XM_017023874.1:c.N/AIntron Variant
SNX29 transcript variant X11XM_017023875.1:c.N/AIntron Variant
SNX29 transcript variant X13XM_017023876.1:c.N/AIntron Variant
SNX29 transcript variant X14XM_017023877.1:c.N/AIntron Variant
SNX29 transcript variant X15XM_017023878.1:c.N/AGenic Upstream Transcript Variant
SNX29 transcript variant X2XR_001752024.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.204C=0.796
1000GenomesAmericanSub694T=0.320C=0.680
1000GenomesEast AsianSub1008T=0.090C=0.910
1000GenomesEuropeSub1006T=0.398C=0.602
1000GenomesGlobalStudy-wide5008T=0.277C=0.723
1000GenomesSouth AsianSub978T=0.410C=0.590
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.418C=0.582
The Genome Aggregation DatabaseAfricanSub8682T=0.247C=0.753
The Genome Aggregation DatabaseAmericanSub836T=0.350C=0.650
The Genome Aggregation DatabaseEast AsianSub1618T=0.091C=0.909
The Genome Aggregation DatabaseEuropeSub18394T=0.426C=0.573
The Genome Aggregation DatabaseGlobalStudy-wide29830T=0.352C=0.647
The Genome Aggregation DatabaseOtherSub300T=0.280C=0.720
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.325C=0.674
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.411C=0.589
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs1830082.8E-05alcoholism (heaviness of drinking)21529783

eQTL of rs183008 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs183008 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr161215627712157047E067-44644
chr161218138712181474E067-20217
chr161218153012181611E067-20080
chr161218170312181843E067-19848
chr161218189312182262E067-19429
chr161218228312182422E067-19269
chr161218566212186867E067-14824
chr161218840912190625E067-11066
chr161219063612191043E067-10648
chr161219104612191925E067-9766
chr161219197912192051E067-9640
chr161220725312208132E0675562
chr161220827912208381E0676588
chr161221384212213924E06712151
chr161223501212235567E06733321
chr161223558412235933E06733893
chr161223598112236118E06734290
chr161224089312241189E06739202
chr161224134812242401E06739657
chr161215627712157047E068-44644
chr161216161812162118E068-39573
chr161218170312181843E068-19848
chr161218189312182262E068-19429
chr161218228312182422E068-19269
chr161218301512183083E068-18608
chr161218566212186867E068-14824
chr161218840912190625E068-11066
chr161219063612191043E068-10648
chr161219104612191925E068-9766
chr161219197912192051E068-9640
chr161220498512205035E0683294
chr161220521912205424E0683528
chr161220545412205532E0683763
chr161220593012206217E0684239
chr161220622012206270E0684529
chr161220629812206428E0684607
chr161220668412206775E0684993
chr161220725312208132E0685562
chr161220827912208381E0686588
chr161224089312241189E06839202
chr161224123312241298E06839542
chr161215302312153586E069-48105
chr161218153012181611E069-20080
chr161218170312181843E069-19848
chr161218189312182262E069-19429
chr161218566212186867E069-14824
chr161218840912190625E069-11066
chr161219063612191043E069-10648
chr161219104612191925E069-9766
chr161219197912192051E069-9640
chr161219214112192251E069-9440
chr161219225212192579E069-9112
chr161219268612192784E069-8907
chr161220725312208132E0695562
chr161220827912208381E0696588
chr161221343912213830E06911748
chr161221384212213924E06912151
chr161223558412235933E06933893
chr161223598112236118E06934290
chr161224089312241189E06939202
chr161218566212186867E070-14824
chr161218840912190625E070-11066
chr161219063612191043E070-10648
chr161219104612191925E070-9766
chr161219197912192051E070-9640
chr161221332712213384E07011636
chr161221400512214944E07012314
chr161221496712215114E07013276
chr161221511712215222E07013426
chr161224089312241189E07039202
chr161224123312241298E07039542
chr161224134812242401E07039657
chr161215302312153586E071-48105
chr161215362512153843E071-47848
chr161216161812162118E071-39573
chr161218445312184530E071-17161
chr161218566212186867E071-14824
chr161218686812186937E071-14754
chr161218696012187046E071-14645
chr161218840912190625E071-11066
chr161219063612191043E071-10648
chr161219104612191925E071-9766
chr161219197912192051E071-9640
chr161219214112192251E071-9440
chr161219225212192579E071-9112
chr161220629812206428E0714607
chr161220668412206775E0714993
chr161220725312208132E0715562
chr161221343912213830E07111748
chr161221384212213924E07112151
chr161221400512214944E07112314
chr161221496712215114E07113276
chr161221511712215222E07113426
chr161221743912217489E07115748
chr161221771612217805E07116025
chr161223091012231525E07129219
chr161223152712232047E07129836
chr161223501212235567E07133321
chr161223558412235933E07133893
chr161224089312241189E07139202
chr161224123312241298E07139542
chr161224134812242401E07139657
chr161224619412246234E07144503
chr161215302312153586E072-48105
chr161215627712157047E072-44644
chr161216161812162118E072-39573
chr161218138712181474E072-20217
chr161218153012181611E072-20080
chr161218170312181843E072-19848
chr161218189312182262E072-19429
chr161218566212186867E072-14824
chr161218840912190625E072-11066
chr161219063612191043E072-10648
chr161219104612191925E072-9766
chr161219197912192051E072-9640
chr161219214112192251E072-9440
chr161219225212192579E072-9112
chr161219268612192784E072-8907
chr161220521912205424E0723528
chr161220545412205532E0723763
chr161220725312208132E0725562
chr161223558412235933E07233893
chr161223598112236118E07234290
chr161224134812242401E07239657
chr161218153012181611E073-20080
chr161218170312181843E073-19848
chr161218566212186867E073-14824
chr161218840912190625E073-11066
chr161219063612191043E073-10648
chr161219104612191925E073-9766
chr161220498512205035E0733294
chr161220521912205424E0733528
chr161221343912213830E07311748
chr161221384212213924E07312151
chr161221400512214944E07312314
chr161221496712215114E07313276
chr161224134812242401E07339657
chr161215302312153586E074-48105
chr161215627712157047E074-44644
chr161218153012181611E074-20080
chr161218170312181843E074-19848
chr161218566212186867E074-14824
chr161218686812186937E074-14754
chr161218696012187046E074-14645
chr161218840912190625E074-11066
chr161219063612191043E074-10648
chr161219104612191925E074-9766
chr161219197912192051E074-9640
chr161220668412206775E0744993
chr161220725312208132E0745562
chr161223501212235567E07433321
chr161223558412235933E07433893
chr161223598112236118E07434290
chr161224123312241298E07439542
chr161224134812242401E07439657
chr161224246112242513E07440770
chr161224302412243135E07441333
chr161224315312243197E07441462
chr161224599212246061E07444301
chr161224619412246234E07444503
chr161224668012246744E07444989
chr161224678112246864E07445090
chr161218840912190625E081-11066
chr161219063612191043E081-10648
chr161219104612191925E081-9766
chr161219214112192251E081-9440
chr161219225212192579E081-9112
chr161220725312208132E0815562
chr161221343912213830E08111748
chr161221384212213924E08112151
chr161221400512214944E08112314
chr161223091012231525E08129219
chr161223152712232047E08129836
chr161224089312241189E08139202
chr161224123312241298E08139542
chr161224134812242401E08139657
chr161218566212186867E082-14824
chr161218686812186937E082-14754
chr161218696012187046E082-14645
chr161218840912190625E082-11066
chr161219063612191043E082-10648
chr161219104612191925E082-9766
chr161220725312208132E0825562
chr161220827912208381E0826588
chr161221400512214944E08212314
chr161223091012231525E08229219
chr161223152712232047E08229836
chr161224089312241189E08239202
chr161224123312241298E08239542
chr161224134812242401E08239657