rs185308415

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0024 (637/26596,GnomAD)
G=0040 (200/5008,1000G)
chr19:40811274 (GRCh38.p7) (19q13.2)
ND
GWASCatalog
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.40811274A>G
GRCh37.p13 chr 19NC_000019.9:g.41317179A>G
CYP2T1P pseudogeneNG_029340.1:g.219T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.994G=0.006
1000GenomesAmericanSub694A=0.910G=0.090
1000GenomesEast AsianSub1008A=0.898G=0.102
1000GenomesEuropeSub1006A=0.996G=0.004
1000GenomesGlobalStudy-wide5008A=0.960G=0.040
1000GenomesSouth AsianSub978A=0.980G=0.020
The Genome Aggregation DatabaseAfricanSub7740A=0.989G=0.011
The Genome Aggregation DatabaseAmericanSub792A=0.890G=0.110
The Genome Aggregation DatabaseEast AsianSub1608A=0.893G=0.107
The Genome Aggregation DatabaseEuropeSub16182A=0.982G=0.017
The Genome Aggregation DatabaseGlobalStudy-wide26596A=0.976G=0.024
The Genome Aggregation DatabaseOtherSub274A=0.990G=0.010
PMID Title Author Journal
27488534Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk.Patel YMCancer Res

P-Value

SNP ID p-value Traits Study
rs1853084153E-09nicotine metabolite ratio in current smokers27488534

eQTL of rs185308415 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs185308415 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr194130919741310378E067-6801
chr194131038641310560E067-6619
chr194131058841311205E067-5974
chr194131122241311679E067-5500
chr194131175641311846E067-5333
chr194131190141311984E067-5195
chr194131405741314164E067-3015
chr194131416541314366E067-2813
chr194131438341314438E067-2741
chr194131454341314844E067-2335
chr194131861441318775E0671435
chr194131889341318990E0671714
chr194131905841319424E0671879
chr194131975741319828E0672578
chr194132413941324179E0676960
chr194132435141324854E0677172
chr194132490741325135E0677728
chr194132542041326011E0678241
chr194132859641329263E06711417
chr194133302141333471E06715842
chr194129725141297337E068-19842
chr194129739141298299E068-18880
chr194129832341298444E068-18735
chr194129847441298695E068-18484
chr194131038641310560E068-6619
chr194131058841311205E068-5974
chr194131122241311679E068-5500
chr194131175641311846E068-5333
chr194131190141311984E068-5195
chr194131335941314035E068-3144
chr194131541741315497E068-1682
chr194131554141315630E068-1549
chr194131567541315793E068-1386
chr194131846141318553E0681282
chr194131861441318775E0681435
chr194131889341318990E0681714
chr194132490741325135E0687728
chr194132542041326011E0688241
chr194132859641329263E06811417
chr194133302141333471E06815842
chr194126943341269558E069-47621
chr194126959341269869E069-47310
chr194130726541307523E069-9656
chr194131058841311205E069-5974
chr194131122241311679E069-5500
chr194131175641311846E069-5333
chr194131190141311984E069-5195
chr194131335941314035E069-3144
chr194131517141315349E069-1830
chr194131541741315497E069-1682
chr194131554141315630E069-1549
chr194131567541315793E069-1386
chr194131905841319424E0691879
chr194131950241319594E0692323
chr194131963241319711E0692453
chr194132366141323817E0696482
chr194132390141323956E0696722
chr194132413941324179E0696960
chr194132435141324854E0697172
chr194132490741325135E0697728
chr194132542041326011E0698241
chr194132836841328433E06911189
chr194132859641329263E06911417
chr194131122241311679E070-5500
chr194131175641311846E070-5333
chr194131190141311984E070-5195
chr194131335941314035E070-3144
chr194131405741314164E070-3015
chr194133924641339303E07022067
chr194126908841269158E071-48021
chr194130919741310378E071-6801
chr194131038641310560E071-6619
chr194131058841311205E071-5974
chr194131122241311679E071-5500
chr194131175641311846E071-5333
chr194131190141311984E071-5195
chr194131335941314035E071-3144
chr194131405741314164E071-3015
chr194131416541314366E071-2813
chr194131438341314438E071-2741
chr194131454341314844E071-2335
chr194131484941314965E071-2214
chr194131517141315349E071-1830
chr194131541741315497E071-1682
chr194131554141315630E071-1549
chr194131567541315793E071-1386
chr194131846141318553E0711282
chr194131861441318775E0711435
chr194131889341318990E0711714
chr194131905841319424E0711879
chr194131950241319594E0712323
chr194131963241319711E0712453
chr194131975741319828E0712578
chr194131989241320080E0712713
chr194132413941324179E0716960
chr194132435141324854E0717172
chr194132490741325135E0717728
chr194132542041326011E0718241
chr194132836841328433E07111189
chr194132859641329263E07111417
chr194132935441329411E07112175
chr194128564141285695E072-31484
chr194128579641285841E072-31338
chr194128588741286023E072-31156
chr194128610641286207E072-30972
chr194129725141297337E072-19842
chr194130919741310378E072-6801
chr194131038641310560E072-6619
chr194131058841311205E072-5974
chr194131122241311679E072-5500
chr194131175641311846E072-5333
chr194131190141311984E072-5195
chr194131335941314035E072-3144
chr194131405741314164E072-3015
chr194131416541314366E072-2813
chr194131438341314438E072-2741
chr194131454341314844E072-2335
chr194131554141315630E072-1549
chr194131567541315793E072-1386
chr194131846141318553E0721282
chr194132413941324179E0726960
chr194132490741325135E0727728
chr194132859641329263E07211417
chr194133302141333471E07215842
chr194133982841339912E07222649
chr194129739141298299E073-18880
chr194129832341298444E073-18735
chr194131058841311205E073-5974
chr194131122241311679E073-5500
chr194131175641311846E073-5333
chr194131190141311984E073-5195
chr194131335941314035E073-3144
chr194131846141318553E0731282
chr194131861441318775E0731435
chr194131889341318990E0731714
chr194131905841319424E0731879
chr194132435141324854E0737172
chr194132490741325135E0737728
chr194132800941328074E07310830
chr194132821741328302E07311038
chr194132836841328433E07311189
chr194132859641329263E07311417
chr194133302141333471E07315842
chr194130919741310378E074-6801
chr194131038641310560E074-6619
chr194131058841311205E074-5974
chr194131122241311679E074-5500
chr194131175641311846E074-5333
chr194131190141311984E074-5195
chr194131335941314035E074-3144
chr194131405741314164E074-3015
chr194131416541314366E074-2813
chr194131438341314438E074-2741
chr194131554141315630E074-1549
chr194131567541315793E074-1386
chr194131846141318553E0741282
chr194131861441318775E0741435
chr194131889341318990E0741714
chr194131905841319424E0741879
chr194131950241319594E0742323
chr194131963241319711E0742453
chr194131975741319828E0742578
chr194131989241320080E0742713
chr194132413941324179E0746960
chr194132435141324854E0747172
chr194132542041326011E0748241
chr194132821741328302E07411038
chr194132836841328433E07411189
chr194132859641329263E07411417
chr194132935441329411E07412175
chr194133302141333471E07415842
chr194133924641339303E07422067
chr194133934641339498E07422167
chr194133982841339912E07422649
chr194135498041355083E07437801
chr194130681641307243E081-9936
chr194130726541307523E081-9656
chr194130919741310378E081-6801
chr194131038641310560E081-6619
chr194131058841311205E081-5974
chr194131122241311679E081-5500
chr194131175641311846E081-5333
chr194131190141311984E081-5195
chr194131204441313329E081-3850
chr194132435141324854E0817172
chr194131122241311679E082-5500
chr194131175641311846E082-5333
chr194131190141311984E082-5195
chr194131846141318553E0821282
chr194131861441318775E0821435
chr194131889341318990E0821714
chr194132366141323817E0826482
chr194132390141323956E0826722
chr194132413941324179E0826960
chr194132435141324854E0827172










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr194128259741285339E067-31840
chr194130378941306736E067-10443
chr194131657041316987E067-192
chr194131703641317275E0670
chr194135433741354458E06737158
chr194135448441354854E06737305
chr194128259741285339E068-31840
chr194130378941306736E068-10443
chr194131657041316987E068-192
chr194131703641317275E0680
chr194128259741285339E069-31840
chr194130378941306736E069-10443
chr194131657041316987E069-192
chr194131703641317275E0690
chr194128259741285339E070-31840
chr194130378941306736E070-10443
chr194131657041316987E070-192
chr194131703641317275E0700
chr194135448441354854E07037305
chr194128259741285339E071-31840
chr194130378941306736E071-10443
chr194131657041316987E071-192
chr194131703641317275E0710
chr194128259741285339E072-31840
chr194130378941306736E072-10443
chr194131657041316987E072-192
chr194131703641317275E0720
chr194135433741354458E07237158
chr194135448441354854E07237305
chr194128259741285339E073-31840
chr194130378941306736E073-10443
chr194131657041316987E073-192
chr194131703641317275E0730
chr194128259741285339E074-31840
chr194130378941306736E074-10443
chr194131657041316987E074-192
chr194131703641317275E0740
chr194128259741285339E081-31840
chr194128259741285339E082-31840
chr194130378941306736E082-10443
chr194131657041316987E082-192
chr194131703641317275E0820