rs1858504

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0389 (11647/29930,GnomAD)
T=0453 (13197/29118,TOPMED)
T=0419 (2100/5008,1000G)
T=0342 (1318/3854,ALSPAC)
T=0316 (1172/3708,TWINSUK)
chr6:19214658 (GRCh38.p7) (6p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.19214658C>T
GRCh37.p13 chr 6NC_000006.11:g.19214889C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.418T=0.582
1000GenomesAmericanSub694C=0.560T=0.440
1000GenomesEast AsianSub1008C=0.732T=0.268
1000GenomesEuropeSub1006C=0.646T=0.354
1000GenomesGlobalStudy-wide5008C=0.581T=0.419
1000GenomesSouth AsianSub978C=0.590T=0.410
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.658T=0.342
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.546T=0.453
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.684T=0.316
PMID Title Author Journal
19581569Genome-wide association study of alcohol dependence.Treutlein JArch Gen Psychiatry

P-Value

SNP ID p-value Traits Study
rs18585047.67E-05alcohol dependence19581569

eQTL of rs1858504 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1858504 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr61922061519220662E0685726
chr61918068719181841E069-33048
chr61918068719181841E071-33048
chr61918068719181841E074-33048