SNP Detail Info-rs186715

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

T==0451 (13448/29810,GnomAD)
T==0394 (11476/29118,TOPMED)
T==0471 (2357/5008,1000G)
G=0469 (1808/3854,ALSPAC)
G=0468 (1734/3708,TWINSUK)

Position: chr19:6878125 (GRCh38.p7) (19p13.3)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 1 Enhancer around

Promoter: 10 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 19	NC_000019.10:g.6878125T>G
GRCh37.p13 chr 19	NC_000019.9:g.6878136T>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.158	G=0.842
1000Genomes	American	Sub	694	T=0.510	G=0.490
1000Genomes	East Asian	Sub	1008	T=0.692	G=0.308
1000Genomes	Europe	Sub	1006	T=0.529	G=0.471
1000Genomes	Global	Study-wide	5008	T=0.471	G=0.529
1000Genomes	South Asian	Sub	978	T=0.580	G=0.420
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.531	G=0.469
The Genome Aggregation Database	African	Sub	8700	T=0.224	G=0.776
The Genome Aggregation Database	American	Sub	834	T=0.530	G=0.470
The Genome Aggregation Database	East Asian	Sub	1610	T=0.678	G=0.322
The Genome Aggregation Database	Europe	Sub	18364	T=0.533	G=0.466
The Genome Aggregation Database	Global	Study-wide	29810	T=0.451	G=0.548
The Genome Aggregation Database	Other	Sub	302	T=0.540	G=0.460
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.394	G=0.605
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.532	G=0.468

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

SNP ID	p-value	Traits	Study
rs186715	2.5E-05	nicotine smoking	19268276

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr19	6862489	6862608	E081	-15528

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr19	6828178	6828292	E068	-49844
chr19	6828300	6828679	E068	-49457
chr19	6862663	6863206	E068	-14930
chr19	6863321	6863940	E068	-14196
chr19	6862663	6863206	E071	-14930
chr19	6863321	6863940	E071	-14196
chr19	6862663	6863206	E072	-14930
chr19	6863321	6863940	E072	-14196
chr19	6862663	6863206	E074	-14930
chr19	6863321	6863940	E074	-14196

rs186715