rs1868009

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0088 (2637/29974,GnomAD)
T=0111 (3244/29118,TOPMED)
T=0094 (473/5008,1000G)
T=0085 (329/3854,ALSPAC)
T=0083 (308/3708,TWINSUK)
chr8:104256541 (GRCh38.p7) (8q22.3)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
21 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.104256541G>T
GRCh37.p13 chr 8NC_000008.10:g.105268769G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.809T=0.191
1000GenomesAmericanSub694G=0.960T=0.040
1000GenomesEast AsianSub1008G=0.958T=0.042
1000GenomesEuropeSub1006G=0.933T=0.067
1000GenomesGlobalStudy-wide5008G=0.906T=0.094
1000GenomesSouth AsianSub978G=0.910T=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.915T=0.085
The Genome Aggregation DatabaseAfricanSub8708G=0.838T=0.162
The Genome Aggregation DatabaseAmericanSub838G=0.940T=0.060
The Genome Aggregation DatabaseEast AsianSub1622G=0.957T=0.043
The Genome Aggregation DatabaseEuropeSub18504G=0.942T=0.057
The Genome Aggregation DatabaseGlobalStudy-wide29974G=0.912T=0.088
The Genome Aggregation DatabaseOtherSub302G=0.900T=0.100
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.888T=0.111
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.917T=0.083
PMID Title Author Journal
22377092ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies.Wang KSDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs18680092.55E-05nicotine dependence (smoking)22377092

eQTL of rs1868009 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1868009 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8105306282105306663E07037513
chr8105306282105306663E08137513
chr8105306282105306663E08237513



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr8105235231105236533E067-32236
chr8105236549105236601E067-32168
chr8105235231105236533E068-32236
chr8105236549105236601E068-32168
chr8105236602105236887E068-31882
chr8105235231105236533E069-32236
chr8105236549105236601E069-32168
chr8105235231105236533E070-32236
chr8105236549105236601E070-32168
chr8105235231105236533E071-32236
chr8105236549105236601E071-32168
chr8105234947105235213E072-33556
chr8105235231105236533E072-32236
chr8105234947105235213E073-33556
chr8105235231105236533E073-32236
chr8105236549105236601E073-32168
chr8105234947105235213E074-33556
chr8105235231105236533E074-32236
chr8105236549105236601E074-32168
chr8105235231105236533E082-32236
chr8105236549105236601E082-32168