rs1868361

Homo sapiens
C>T
KCCAT333 : Intron Variant
LOC105375172 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0156 (4668/29910,GnomAD)
T=0134 (3905/29118,TOPMED)
T=0210 (1054/5008,1000G)
T=0184 (711/3854,ALSPAC)
T=0192 (713/3708,TWINSUK)
chr7:17456045 (GRCh38.p7) (7p21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.17456045C>T
GRCh37.p13 chr 7NC_000007.13:g.17495669C>T

Gene: KCCAT333, renal clear cell carcinoma-associated transcript 333(plus strand)

Molecule type Change Amino acid[Codon] SO Term
KCCAT333 transcript variant 1NR_110014.1:n.N/AIntron Variant
KCCAT333 transcript variant 2NR_110015.1:n.N/AIntron Variant

Gene: LOC105375172, uncharacterized LOC105375172(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105375172 transcriptXR_001745108.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.927T=0.073
1000GenomesAmericanSub694C=0.670T=0.330
1000GenomesEast AsianSub1008C=0.671T=0.329
1000GenomesEuropeSub1006C=0.839T=0.161
1000GenomesGlobalStudy-wide5008C=0.790T=0.210
1000GenomesSouth AsianSub978C=0.760T=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.816T=0.184
The Genome Aggregation DatabaseAfricanSub8714C=0.911T=0.089
The Genome Aggregation DatabaseAmericanSub836C=0.680T=0.320
The Genome Aggregation DatabaseEast AsianSub1604C=0.716T=0.284
The Genome Aggregation DatabaseEuropeSub18456C=0.830T=0.169
The Genome Aggregation DatabaseGlobalStudy-wide29910C=0.843T=0.156
The Genome Aggregation DatabaseOtherSub300C=0.880T=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.865T=0.134
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.808T=0.192
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs18683610.000518alcohol dependence20201924

eQTL of rs1868361 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1868361 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr71753675117536801E08241082
chr71753681417536961E08241145
chr71753707017537125E08241401
chr71753715017537230E08241481
chr71753731217537718E08241643