rs1868534

Homo sapiens
T>G
NTM : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0471 (14080/29862,GnomAD)
G=0492 (14350/29118,TOPMED)
G=0437 (2187/5008,1000G)
G=0466 (1797/3854,ALSPAC)
G=0450 (1669/3708,TWINSUK)
chr11:132224572 (GRCh38.p7) (11q25)
ND
GWASdb2
1   publication(s)
See rs on genome
262 Enhancers around
3 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.132224572T>G
GRCh37.p13 chr 11NC_000011.9:g.132094466T>G

Gene: NTM, neurotrimin(plus strand)

Molecule type Change Amino acid[Codon] SO Term
NTM transcript variant 2NM_001048209.1:c.N/AIntron Variant
NTM transcript variant 3NM_001144058.1:c.N/AIntron Variant
NTM transcript variant 4NM_001144059.1:c.N/AIntron Variant
NTM transcript variant 1NM_016522.2:c.N/AIntron Variant
NTM transcript variant X9XM_005271580.3:c.N/AIntron Variant
NTM transcript variant X6XM_005271581.3:c.N/AIntron Variant
NTM transcript variant X12XM_005271582.3:c.N/AIntron Variant
NTM transcript variant X13XM_006718855.3:c.N/AIntron Variant
NTM transcript variant X23XM_006718857.3:c.N/AIntron Variant
NTM transcript variant X16XM_011542861.2:c.N/AIntron Variant
NTM transcript variant X1XM_017017851.1:c.N/AIntron Variant
NTM transcript variant X3XM_017017852.1:c.N/AIntron Variant
NTM transcript variant X4XM_017017853.1:c.N/AIntron Variant
NTM transcript variant X4XM_017017854.1:c.N/AIntron Variant
NTM transcript variant X7XM_017017855.1:c.N/AIntron Variant
NTM transcript variant X8XM_017017856.1:c.N/AIntron Variant
NTM transcript variant X11XM_017017857.1:c.N/AIntron Variant
NTM transcript variant X14XM_017017858.1:c.N/AIntron Variant
NTM transcript variant X11XM_017017859.1:c.N/AIntron Variant
NTM transcript variant X16XM_017017860.1:c.N/AIntron Variant
NTM transcript variant X17XM_017017861.1:c.N/AIntron Variant
NTM transcript variant X18XM_017017862.1:c.N/AIntron Variant
NTM transcript variant X15XM_017017863.1:c.N/AIntron Variant
NTM transcript variant X21XM_017017864.1:c.N/AIntron Variant
NTM transcript variant X22XM_017017865.1:c.N/AIntron Variant
NTM transcript variant X24XM_017017866.1:c.N/AIntron Variant
NTM transcript variant X29XM_017017867.1:c.N/AIntron Variant
NTM transcript variant X1XR_001747893.1:n.N/AIntron Variant
NTM transcript variant X8XR_001747894.1:n.N/AIntron Variant
NTM transcript variant X25XR_001747895.1:n.N/AIntron Variant
NTM transcript variant X20XR_001747896.1:n.N/AIntron Variant
NTM transcript variant X27XR_001747897.1:n.N/AIntron Variant
NTM transcript variant X28XR_001747898.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.430G=0.570
1000GenomesAmericanSub694T=0.520G=0.480
1000GenomesEast AsianSub1008T=0.809G=0.191
1000GenomesEuropeSub1006T=0.517G=0.483
1000GenomesGlobalStudy-wide5008T=0.563G=0.437
1000GenomesSouth AsianSub978T=0.570G=0.430
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.534G=0.466
The Genome Aggregation DatabaseAfricanSub8680T=0.438G=0.562
The Genome Aggregation DatabaseAmericanSub838T=0.550G=0.450
The Genome Aggregation DatabaseEast AsianSub1612T=0.803G=0.197
The Genome Aggregation DatabaseEuropeSub18430T=0.547G=0.452
The Genome Aggregation DatabaseGlobalStudy-wide29862T=0.528G=0.471
The Genome Aggregation DatabaseOtherSub302T=0.440G=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.507G=0.492
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.550G=0.450
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs18685340.000529nicotine smoking19268276

eQTL of rs1868534 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1868534 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11132056696132056866E067-37600
chr11132057090132057147E067-37319
chr11132057458132057550E067-36916
chr11132084011132084082E067-10384
chr11132084118132084168E067-10298
chr11132084171132084221E067-10245
chr11132085134132085218E067-9248
chr11132105213132105322E06710747
chr11132108321132108371E06713855
chr11132108481132108535E06714015
chr11132108543132108607E06714077
chr11132108682132108732E06714216
chr11132108733132108783E06714267
chr11132111824132111876E06717358
chr11132111906132112125E06717440
chr11132115024132115559E06720558
chr11132115715132115883E06721249
chr11132115974132116174E06721508
chr11132116268132116328E06721802
chr11132116433132116516E06721967
chr11132116713132116800E06722247
chr11132118383132118897E06723917
chr11132119018132119111E06724552
chr11132127897132128040E06733431
chr11132128071132128131E06733605
chr11132084011132084082E068-10384
chr11132084118132084168E068-10298
chr11132084171132084221E068-10245
chr11132084594132084688E068-9778
chr11132099859132099949E0685393
chr11132108321132108371E06813855
chr11132108481132108535E06814015
chr11132108543132108607E06814077
chr11132111906132112125E06817440
chr11132113842132114022E06819376
chr11132114545132114618E06820079
chr11132114680132114937E06820214
chr11132115024132115559E06820558
chr11132115715132115883E06821249
chr11132115974132116174E06821508
chr11132118009132118224E06823543
chr11132118383132118897E06823917
chr11132125234132125293E06830768
chr11132056696132056866E069-37600
chr11132057090132057147E069-37319
chr11132057458132057550E069-36916
chr11132057637132058033E069-36433
chr11132084011132084082E069-10384
chr11132084118132084168E069-10298
chr11132084171132084221E069-10245
chr11132084594132084688E069-9778
chr11132097787132097846E0693321
chr11132108321132108371E06913855
chr11132108481132108535E06914015
chr11132108543132108607E06914077
chr11132108682132108732E06914216
chr11132108733132108783E06914267
chr11132111824132111876E06917358
chr11132111906132112125E06917440
chr11132112634132112834E06918168
chr11132112896132112947E06918430
chr11132114545132114618E06920079
chr11132114680132114937E06920214
chr11132115024132115559E06920558
chr11132115715132115883E06921249
chr11132115974132116174E06921508
chr11132116713132116800E06922247
chr11132117805132117845E06923339
chr11132118009132118224E06923543
chr11132118383132118897E06923917
chr11132119018132119111E06924552
chr11132125923132126010E06931457
chr11132127897132128040E06933431
chr11132055657132055919E070-38547
chr11132056093132056405E070-38061
chr11132056696132056866E070-37600
chr11132057090132057147E070-37319
chr11132057458132057550E070-36916
chr11132057637132058033E070-36433
chr11132059277132059317E070-35149
chr11132059395132059449E070-35017
chr11132071139132071189E070-23277
chr11132071453132071537E070-22929
chr11132107036132107178E07012570
chr11132107545132107595E07013079
chr11132107704132108018E07013238
chr11132108321132108371E07013855
chr11132111824132111876E07017358
chr11132111906132112125E07017440
chr11132112471132112605E07018005
chr11132112634132112834E07018168
chr11132112896132112947E07018430
chr11132113842132114022E07019376
chr11132114545132114618E07020079
chr11132114680132114937E07020214
chr11132115024132115559E07020558
chr11132115715132115883E07021249
chr11132115974132116174E07021508
chr11132116268132116328E07021802
chr11132116433132116516E07021967
chr11132116713132116800E07022247
chr11132117084132117181E07022618
chr11132117412132117456E07022946
chr11132117805132117845E07023339
chr11132118009132118224E07023543
chr11132118383132118897E07023917
chr11132119018132119111E07024552
chr11132119289132119339E07024823
chr11132127897132128040E07033431
chr11132128071132128131E07033605
chr11132131449132131620E07036983
chr11132131924132131974E07037458
chr11132083054132083140E071-11326
chr11132084011132084082E071-10384
chr11132084118132084168E071-10298
chr11132084171132084221E071-10245
chr11132084594132084688E071-9778
chr11132085134132085218E071-9248
chr11132097787132097846E0713321
chr11132101857132101918E0717391
chr11132101968132102067E0717502
chr11132107704132108018E07113238
chr11132108321132108371E07113855
chr11132108481132108535E07114015
chr11132108543132108607E07114077
chr11132111824132111876E07117358
chr11132111906132112125E07117440
chr11132112471132112605E07118005
chr11132113842132114022E07119376
chr11132114545132114618E07120079
chr11132114680132114937E07120214
chr11132115024132115559E07120558
chr11132115715132115883E07121249
chr11132115974132116174E07121508
chr11132116268132116328E07121802
chr11132117805132117845E07123339
chr11132118009132118224E07123543
chr11132124052132124102E07129586
chr11132124125132124175E07129659
chr11132124332132124390E07129866
chr11132126388132127077E07131922
chr11132127897132128040E07133431
chr11132128071132128131E07133605
chr11132138927132138977E07144461
chr11132139211132139321E07144745
chr11132084011132084082E072-10384
chr11132084118132084168E072-10298
chr11132084171132084221E072-10245
chr11132084594132084688E072-9778
chr11132097787132097846E0723321
chr11132107545132107595E07213079
chr11132107704132108018E07213238
chr11132108321132108371E07213855
chr11132108481132108535E07214015
chr11132108543132108607E07214077
chr11132111824132111876E07217358
chr11132111906132112125E07217440
chr11132113842132114022E07219376
chr11132114545132114618E07220079
chr11132114680132114937E07220214
chr11132115024132115559E07220558
chr11132115715132115883E07221249
chr11132115974132116174E07221508
chr11132116268132116328E07221802
chr11132118009132118224E07223543
chr11132118383132118897E07223917
chr11132126388132127077E07231922
chr11132127897132128040E07233431
chr11132131201132131251E07236735
chr11132056696132056866E073-37600
chr11132057090132057147E073-37319
chr11132057458132057550E073-36916
chr11132084594132084688E073-9778
chr11132086256132086306E073-8160
chr11132087787132088054E073-6412
chr11132090863132090913E073-3553
chr11132099859132099949E0735393
chr11132108321132108371E07313855
chr11132108481132108535E07314015
chr11132108543132108607E07314077
chr11132108682132108732E07314216
chr11132108733132108783E07314267
chr11132114545132114618E07320079
chr11132114680132114937E07320214
chr11132115024132115559E07320558
chr11132115715132115883E07321249
chr11132115974132116174E07321508
chr11132116268132116328E07321802
chr11132126388132127077E07331922
chr11132131201132131251E07336735
chr11132084011132084082E074-10384
chr11132084118132084168E074-10298
chr11132084171132084221E074-10245
chr11132084594132084688E074-9778
chr11132107704132108018E07413238
chr11132108321132108371E07413855
chr11132108481132108535E07414015
chr11132108543132108607E07414077
chr11132111824132111876E07417358
chr11132111906132112125E07417440
chr11132114545132114618E07420079
chr11132114680132114937E07420214
chr11132115024132115559E07420558
chr11132115715132115883E07421249
chr11132115974132116174E07421508
chr11132116268132116328E07421802
chr11132116433132116516E07421967
chr11132116713132116800E07422247
chr11132118009132118224E07423543
chr11132118383132118897E07423917
chr11132127897132128040E07433431
chr11132128071132128131E07433605
chr11132054194132054303E081-40163
chr11132056093132056405E081-38061
chr11132056696132056866E081-37600
chr11132057090132057147E081-37319
chr11132057458132057550E081-36916
chr11132087375132087595E081-6871
chr11132087787132088054E081-6412
chr11132088250132088405E081-6061
chr11132111824132111876E08117358
chr11132111906132112125E08117440
chr11132112471132112605E08118005
chr11132112634132112834E08118168
chr11132113842132114022E08119376
chr11132114545132114618E08120079
chr11132114680132114937E08120214
chr11132115024132115559E08120558
chr11132115715132115883E08121249
chr11132115974132116174E08121508
chr11132116268132116328E08121802
chr11132117805132117845E08123339
chr11132118009132118224E08123543
chr11132118383132118897E08123917
chr11132119018132119111E08124552
chr11132119289132119339E08124823
chr11132126388132127077E08131922
chr11132127897132128040E08133431
chr11132131201132131251E08136735
chr11132138336132138456E08143870
chr11132087787132088054E082-6412
chr11132088250132088405E082-6061
chr11132088690132088816E082-5650
chr11132101857132101918E0827391
chr11132101968132102067E0827502
chr11132111824132111876E08217358
chr11132111906132112125E08217440
chr11132113842132114022E08219376
chr11132114545132114618E08220079
chr11132114680132114937E08220214
chr11132115024132115559E08220558
chr11132115715132115883E08221249
chr11132115974132116174E08221508
chr11132116268132116328E08221802
chr11132116433132116516E08221967
chr11132116713132116800E08222247
chr11132118009132118224E08223543
chr11132118383132118897E08223917
chr11132125923132126010E08231457
chr11132126388132127077E08231922
chr11132127897132128040E08233431
chr11132128071132128131E08233605










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr11132082066132082153E073-12313
chr11132082455132082513E073-11953
chr11132082789132083025E073-11441