rs1872052

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0454 (13590/29930,GnomAD)
C=0432 (12590/29118,TOPMED)
C=0441 (2208/5008,1000G)
C=0499 (1922/3854,ALSPAC)
T==0488 (1811/3708,TWINSUK)
chr15:93209649 (GRCh38.p7) (15q26.1)
OD
GWASCatalog
3   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.93209649T>C
GRCh37.p13 chr 15NC_000015.9:g.93752878T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.688C=0.312
1000GenomesAmericanSub694T=0.700C=0.300
1000GenomesEast AsianSub1008T=0.451C=0.549
1000GenomesEuropeSub1006T=0.509C=0.491
1000GenomesGlobalStudy-wide5008T=0.559C=0.441
1000GenomesSouth AsianSub978T=0.450C=0.550
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.501C=0.499
The Genome Aggregation DatabaseAfricanSub8714T=0.660C=0.340
The Genome Aggregation DatabaseAmericanSub834T=0.740C=0.260
The Genome Aggregation DatabaseEast AsianSub1618T=0.440C=0.560
The Genome Aggregation DatabaseEuropeSub18462T=0.492C=0.507
The Genome Aggregation DatabaseGlobalStudy-wide29930T=0.545C=0.454
The Genome Aggregation DatabaseOtherSub302T=0.570C=0.430
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.567C=0.432
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.488C=0.512
PMID Title Author Journal
21302341Replicated genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs.Drgon TAm J Med Genet B Neuropsychiatr Genet
21818250Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence.Johnson CPLoS One
29478698Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.Cheng ZBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs18720522E-07Opioid dependence29478698

eQTL of rs1872052 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1872052 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159372598293726796E070-26082
chr159373281093733181E070-19697
chr159378495493785731E07032076
chr159378577293785865E07032894
chr159375667293756916E0823794
chr159375699993757039E0824121
chr159375706293757253E0824184
chr159375730093757613E0824422