rs1873117

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0056 (1677/29930,GnomAD)
C=0050 (1473/29116,TOPMED)
C=0026 (131/5008,1000G)
C=0066 (254/3854,ALSPAC)
C=0068 (252/3708,TWINSUK)
chr2:36036324 (GRCh38.p7) (2p22.3)
ND
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.36036324T>C
GRCh37.p13 chr 2NC_000002.11:g.36263467T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.996C=0.004
1000GenomesAmericanSub694T=0.970C=0.030
1000GenomesEast AsianSub1008T=0.999C=0.001
1000GenomesEuropeSub1006T=0.911C=0.089
1000GenomesGlobalStudy-wide5008T=0.974C=0.026
1000GenomesSouth AsianSub978T=0.990C=0.010
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.934C=0.066
The Genome Aggregation DatabaseAfricanSub8728T=0.985C=0.015
The Genome Aggregation DatabaseAmericanSub836T=0.960C=0.040
The Genome Aggregation DatabaseEast AsianSub1602T=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18462T=0.918C=0.081
The Genome Aggregation DatabaseGlobalStudy-wide29930T=0.944C=0.056
The Genome Aggregation DatabaseOtherSub302T=0.960C=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.949C=0.050
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.932C=0.068
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs18731170.000384nicotine dependence17158188

eQTL of rs1873117 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1873117 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr23627066536270715E0677198
chr23621418736214645E068-48822
chr23621471336214944E068-48523
chr23627066536270715E0697198
chr23627034936270442E0716882
chr23627066536270715E0717198
chr23630209736302271E08238630