rs1875144

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0323 (9674/29898,GnomAD)
T==0257 (7501/29118,TOPMED)
T==0317 (1588/5008,1000G)
T==0412 (1586/3854,ALSPAC)
T==0410 (1521/3708,TWINSUK)
chr12:117037373 (GRCh38.p7) (12q24.22)
AD
GWASdb2
1   publication(s)
See rs on genome
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.117037373T>C
GRCh37.p13 chr 12NC_000012.11:g.117475178T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.035C=0.965
1000GenomesAmericanSub694T=0.530C=0.470
1000GenomesEast AsianSub1008T=0.438C=0.562
1000GenomesEuropeSub1006T=0.415C=0.585
1000GenomesGlobalStudy-wide5008T=0.317C=0.683
1000GenomesSouth AsianSub978T=0.320C=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.412C=0.588
The Genome Aggregation DatabaseAfricanSub8706T=0.088C=0.912
The Genome Aggregation DatabaseAmericanSub836T=0.520C=0.480
The Genome Aggregation DatabaseEast AsianSub1608T=0.430C=0.570
The Genome Aggregation DatabaseEuropeSub18446T=0.416C=0.583
The Genome Aggregation DatabaseGlobalStudy-wide29898T=0.323C=0.676
The Genome Aggregation DatabaseOtherSub302T=0.310C=0.690
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.257C=0.742
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.410C=0.590
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs18751449.37E-05alcohol dependence21703634

eQTL of rs1875144 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1875144 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr12117434488117434809E067-40369
chr12117439678117440525E067-34653
chr12117463151117463999E067-11179
chr12117464281117464606E067-10572
chr12117470313117471198E067-3980
chr12117472535117472715E067-2463
chr12117482675117484184E0677497
chr12117499018117499068E06723840
chr12117449848117449904E068-25274
chr12117449952117450040E068-25138
chr12117450136117450543E068-24635
chr12117463151117463999E068-11179
chr12117470313117471198E068-3980
chr12117475558117475682E068380
chr12117475712117475773E068534
chr12117475829117475879E068651
chr12117475914117475969E068736
chr12117476087117476179E068909
chr12117477826117477918E0682648
chr12117482675117484184E0687497
chr12117484194117484350E0689016
chr12117486768117487240E06811590
chr12117487321117487398E06812143
chr12117488739117489135E06813561
chr12117489190117489749E06814012
chr12117496692117496829E06821514
chr12117496868117496988E06821690
chr12117496996117497095E06821818
chr12117497103117497232E06821925
chr12117497266117497342E06822088
chr12117497934117497994E06822756
chr12117499018117499068E06823840
chr12117499210117499407E06824032
chr12117499431117499481E06824253
chr12117499510117499662E06824332
chr12117499698117499797E06824520
chr12117499823117499873E06824645
chr12117500375117500453E06825197
chr12117500461117501790E06825283
chr12117505577117505677E06830399
chr12117514686117515217E06839508
chr12117522362117522584E06847184
chr12117522635117522725E06847457
chr12117522970117523079E06847792
chr12117523367117523498E06848189
chr12117523609117523679E06848431
chr12117523889117523933E06848711
chr12117524675117524914E06849497
chr12117524962117525070E06849784
chr12117434488117434809E069-40369
chr12117470313117471198E069-3980
chr12117482675117484184E0697497
chr12117499018117499068E06923840
chr12117499210117499407E06924032
chr12117500375117500453E06925197
chr12117436039117436177E070-39001
chr12117439378117439565E070-35613
chr12117439678117440525E070-34653
chr12117440565117440696E070-34482
chr12117440876117441225E070-33953
chr12117441418117441586E070-33592
chr12117441659117441760E070-33418
chr12117441778117441834E070-33344
chr12117441907117441970E070-33208
chr12117442365117442470E070-32708
chr12117447635117447991E070-27187
chr12117448049117448126E070-27052
chr12117448136117448258E070-26920
chr12117448312117448399E070-26779
chr12117448606117448712E070-26466
chr12117448728117448873E070-26305
chr12117456934117456988E070-18190
chr12117457233117457293E070-17885
chr12117457964117458024E070-17154
chr12117458116117458166E070-17012
chr12117458171117458294E070-16884
chr12117458478117458528E070-16650
chr12117458586117458956E070-16222
chr12117459650117459759E070-15419
chr12117459947117460000E070-15178
chr12117460206117460288E070-14890
chr12117460310117460379E070-14799
chr12117463151117463999E070-11179
chr12117470313117471198E070-3980
chr12117472535117472715E070-2463
chr12117472762117472885E070-2293
chr12117473150117473267E070-1911
chr12117473269117473373E070-1805
chr12117473397117473484E070-1694
chr12117478562117478732E0703384
chr12117482675117484184E0707497
chr12117484194117484350E0709016
chr12117484464117484524E0709286
chr12117489834117489950E07014656
chr12117490173117490282E07014995
chr12117490288117490315E07015110
chr12117490321117490488E07015143
chr12117490602117490758E07015424
chr12117496692117496829E07021514
chr12117496868117496988E07021690
chr12117496996117497095E07021818
chr12117497103117497232E07021925
chr12117497266117497342E07022088
chr12117497934117497994E07022756
chr12117498136117498926E07022958
chr12117448606117448712E071-26466
chr12117448728117448873E071-26305
chr12117470102117470303E071-4875
chr12117482675117484184E0717497
chr12117484194117484350E0719016
chr12117486360117486669E07111182
chr12117498136117498926E07122958
chr12117523367117523498E07148189
chr12117434488117434809E072-40369
chr12117435017117435150E072-40028
chr12117435182117435276E072-39902
chr12117463151117463999E072-11179
chr12117470313117471198E072-3980
chr12117472535117472715E072-2463
chr12117476907117477030E0721729
chr12117477156117477260E0721978
chr12117477394117477434E0722216
chr12117477826117477918E0722648
chr12117482675117484184E0727497
chr12117498136117498926E07222958
chr12117522006117522163E07246828
chr12117522970117523079E07247792
chr12117523367117523498E07248189
chr12117524675117524914E07249497
chr12117463151117463999E073-11179
chr12117475829117475879E073651
chr12117475914117475969E073736
chr12117476087117476179E073909
chr12117477826117477918E0732648
chr12117482675117484184E0737497
chr12117498136117498926E07322958
chr12117499018117499068E07323840
chr12117499210117499407E07324032
chr12117499431117499481E07324253
chr12117499510117499662E07324332
chr12117429211117429907E074-45271
chr12117434488117434809E074-40369
chr12117437035117437085E074-38093
chr12117437496117437607E074-37571
chr12117439678117440525E074-34653
chr12117463151117463999E074-11179
chr12117498136117498926E07422958
chr12117499018117499068E07423840
chr12117502184117502344E07427006
chr12117439678117440525E081-34653
chr12117456934117456988E081-18190
chr12117457233117457293E081-17885
chr12117457964117458024E081-17154
chr12117458116117458166E081-17012
chr12117458171117458294E081-16884
chr12117458478117458528E081-16650
chr12117463151117463999E081-11179
chr12117472535117472715E081-2463
chr12117472762117472885E081-2293
chr12117473150117473267E081-1911
chr12117482675117484184E0817497
chr12117484194117484350E0819016
chr12117484464117484524E0819286
chr12117488314117488602E08113136
chr12117488739117489135E08113561
chr12117491685117491885E08116507
chr12117497934117497994E08122756
chr12117498136117498926E08122958
chr12117499018117499068E08123840
chr12117439678117440525E082-34653
chr12117440565117440696E082-34482
chr12117440876117441225E082-33953
chr12117456934117456988E082-18190
chr12117457233117457293E082-17885
chr12117472535117472715E082-2463
chr12117472762117472885E082-2293
chr12117474386117474464E082-714
chr12117474480117474540E082-638
chr12117482675117484184E0827497
chr12117484194117484350E0829016
chr12117490288117490315E08215110
chr12117497934117497994E08222756
chr12117498136117498926E08222958










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr12117433936117434295E067-40883
chr12117434350117434443E067-40735
chr12117433936117434295E068-40883
chr12117433936117434295E071-40883
chr12117434350117434443E071-40735
chr12117433936117434295E072-40883
chr12117434350117434443E072-40735
chr12117433936117434295E074-40883
chr12117434350117434443E074-40735