SNP Detail Info-rs1877026

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.62845073A>G
GRCh37.p13 chr 2	NC_000002.11:g.63072208A>G
EHBP1 RefSeqGene	NG_016758.1:g.176223A>G

Gene: EHBP1, EH domain binding protein 1(plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
EHBP1 transcript variant 2	NM_001142614.1:c.	N/A	Intron Variant
EHBP1 transcript variant 3	NM_001142615.2:c.	N/A	Intron Variant
EHBP1 transcript variant 4	NM_001142616.1:c.	N/A	Intron Variant
EHBP1 transcript variant 1	NM_015252.3:c.	N/A	Intron Variant
EHBP1 transcript variant X1	XM_005264225.2:c.	N/A	Intron Variant
EHBP1 transcript variant X5	XM_005264226.2:c.	N/A	Intron Variant
EHBP1 transcript variant X4	XM_005264227.1:c.	N/A	Intron Variant
EHBP1 transcript variant X23	XM_005264228.2:c.	N/A	Intron Variant
EHBP1 transcript variant X15	XM_006711971.2:c.	N/A	Intron Variant
EHBP1 transcript variant X2	XM_011532713.2:c.	N/A	Intron Variant
EHBP1 transcript variant X3	XM_011532714.2:c.	N/A	Intron Variant
EHBP1 transcript variant X7	XM_011532715.2:c.	N/A	Intron Variant
EHBP1 transcript variant X8	XM_011532716.2:c.	N/A	Intron Variant
EHBP1 transcript variant X17	XM_011532717.1:c.	N/A	Intron Variant
EHBP1 transcript variant X22	XM_011532718.2:c.	N/A	Intron Variant
EHBP1 transcript variant X4	XM_017003643.1:c.	N/A	Intron Variant
EHBP1 transcript variant X6	XM_017003644.1:c.	N/A	Intron Variant
EHBP1 transcript variant X9	XM_017003645.1:c.	N/A	Intron Variant
EHBP1 transcript variant X10	XM_017003646.1:c.	N/A	Intron Variant
EHBP1 transcript variant X12	XM_017003647.1:c.	N/A	Intron Variant
EHBP1 transcript variant X13	XM_017003648.1:c.	N/A	Intron Variant
EHBP1 transcript variant X14	XM_017003649.1:c.	N/A	Intron Variant
EHBP1 transcript variant X16	XM_017003650.1:c.	N/A	Intron Variant
EHBP1 transcript variant X18	XM_017003651.1:c.	N/A	Intron Variant
EHBP1 transcript variant X19	XM_017003652.1:c.	N/A	Intron Variant
EHBP1 transcript variant X20	XM_017003653.1:c.	N/A	Intron Variant
EHBP1 transcript variant X21	XM_017003654.1:c.	N/A	Intron Variant
EHBP1 transcript variant X24	XM_017003655.1:c.	N/A	Intron Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.009	G=0.991
1000Genomes	American	Sub	694	A=0.160	G=0.840
1000Genomes	East Asian	Sub	1008	A=0.502	G=0.498
1000Genomes	Europe	Sub	1006	A=0.136	G=0.864
1000Genomes	Global	Study-wide	5008	A=0.233	G=0.767
1000Genomes	South Asian	Sub	978	A=0.410	G=0.590
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.161	G=0.839
The Genome Aggregation Database	African	Sub	8712	A=0.036	G=0.964
The Genome Aggregation Database	American	Sub	828	A=0.230	G=0.770
The Genome Aggregation Database	East Asian	Sub	1614	A=0.471	G=0.529
The Genome Aggregation Database	Europe	Sub	18334	A=0.173	G=0.826
The Genome Aggregation Database	Global	Study-wide	29790	A=0.149	G=0.850
The Genome Aggregation Database	Other	Sub	302	A=0.050	G=0.950
Trans-Omics for Precision Medicine	Global	Study-wide	29116	A=0.099	G=0.900
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.145	G=0.855

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

P-Value

SNP ID	p-value	Traits	Study
rs1877026	2.06E-05	alcohol and nictotine co-dependence	20158304

eQTL of rs1877026 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs1877026 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	63052860	63052910	E082	-19298
chr2	63052965	63053033	E082	-19175

rs1877026

Genomic Coordinates

Gene: EHBP1, EH domain binding protein 1(plus strand)

Population Frequency

P-Value

eQTL of rs1877026 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs1877026 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)