| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 1 | NC_000001.11:g.29661757C>A |
| GRCh38.p7 chr 1 | NC_000001.11:g.29661757C>G |
| GRCh37.p13 chr 1 | NC_000001.10:g.30134604C>A |
| GRCh37.p13 chr 1 | NC_000001.10:g.30134604C>G |
| Molecule type | Change | Amino acid[Codon] | SO Term |
|---|---|---|---|
| LOC107984934 transcript variant X1 | XR_001737956.1:n. | N/A | Intron Variant |
| LOC107984934 transcript variant X2 | XR_001737957.1:n. | N/A | Intron Variant |
| LOC107984934 transcript variant X3 | XR_001737958.1:n. | N/A | Intron Variant |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | C=0.551 | A=0.449 |
| 1000Genomes | American | Sub | 694 | C=0.480 | A=0.520 |
| 1000Genomes | East Asian | Sub | 1008 | C=0.383 | A=0.617 |
| 1000Genomes | Europe | Sub | 1006 | C=0.566 | A=0.434 |
| 1000Genomes | Global | Study-wide | 5008 | C=0.489 | A=0.511 |
| 1000Genomes | South Asian | Sub | 978 | C=0.440 | A=0.560 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | C=0.546 | A=0.454 |
| The Genome Aggregation Database | African | Sub | 8690 | C=0.551 | A=0.449 |
| The Genome Aggregation Database | American | Sub | 836 | C=0.470 | A=0.53, |
| The Genome Aggregation Database | East Asian | Sub | 1612 | C=0.370 | A=0.630 |
| The Genome Aggregation Database | Europe | Sub | 18430 | C=0.571 | A=0.428 |
| The Genome Aggregation Database | Global | Study-wide | 29870 | C=0.552 | A=0.447 |
| The Genome Aggregation Database | Other | Sub | 302 | C=0.640 | A=0.36, |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | C=0.537 | A=0.462 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | C=0.546 | A=0.454 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 20158304 | A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. | Lind PA | Twin Res Hum Genet |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs187954 | 8.65E-06 | alcohol and nictotine co-dependence | 20158304 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue | |
|---|---|---|---|---|---|---|---|
| There is no eQTL annotation for this SNP | |||||||
| Probe ID | Position | Gene | beta | p-value | |||
|---|---|---|---|---|---|---|---|
| There is no meQTL annotation for this SNP | |||||||
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr1 | 155296008 | 155296088 | E067 | -9016 |
| chr1 | 155348031 | 155348195 | E067 | 42927 |
| chr1 | 155348909 | 155349103 | E067 | 43805 |
| chr1 | 155349250 | 155349910 | E067 | 44146 |
| chr1 | 155280466 | 155280524 | E069 | -24580 |
| chr1 | 155280591 | 155280654 | E069 | -24450 |
| chr1 | 155295538 | 155295939 | E069 | -9165 |
| chr1 | 155348031 | 155348195 | E069 | 42927 |
| chr1 | 155348909 | 155349103 | E069 | 43805 |
| chr1 | 155349250 | 155349910 | E069 | 44146 |
| chr1 | 155289427 | 155289477 | E070 | -15627 |
| chr1 | 155289725 | 155289775 | E070 | -15329 |
| chr1 | 155296358 | 155296428 | E070 | -8676 |
| chr1 | 155283091 | 155283479 | E071 | -21625 |
| chr1 | 155289810 | 155290051 | E071 | -15053 |
| chr1 | 155348031 | 155348195 | E071 | 42927 |
| chr1 | 155348909 | 155349103 | E071 | 43805 |
| chr1 | 155349250 | 155349910 | E071 | 44146 |
| chr1 | 155348031 | 155348195 | E072 | 42927 |
| chr1 | 155348909 | 155349103 | E072 | 43805 |
| chr1 | 155349250 | 155349910 | E072 | 44146 |
| chr1 | 155283091 | 155283479 | E073 | -21625 |
| chr1 | 155289725 | 155289775 | E073 | -15329 |
| chr1 | 155295538 | 155295939 | E073 | -9165 |
| chr1 | 155280466 | 155280524 | E074 | -24580 |
| chr1 | 155280591 | 155280654 | E074 | -24450 |
| chr1 | 155348909 | 155349103 | E074 | 43805 |
| chr1 | 155349250 | 155349910 | E074 | 44146 |
| chr1 | 155280466 | 155280524 | E081 | -24580 |
| chr1 | 155280591 | 155280654 | E081 | -24450 |
| chr1 | 155289810 | 155290051 | E081 | -15053 |
| chr1 | 155295538 | 155295939 | E081 | -9165 |
| chr1 | 155296008 | 155296088 | E081 | -9016 |
| chr1 | 155296122 | 155296232 | E081 | -8872 |
| chr1 | 155280466 | 155280524 | E082 | -24580 |
| chr1 | 155280591 | 155280654 | E082 | -24450 |
| chr1 | 155295538 | 155295939 | E082 | -9165 |
| chr1 | 155296008 | 155296088 | E082 | -9016 |
| chr1 | 155296122 | 155296232 | E082 | -8872 |
| chr1 | 155296358 | 155296428 | E082 | -8676 |
| Chromosome | Start | End | Region | Distance(-/+:Up/Downstream) |
|---|---|---|---|---|
| chr1 | 155264992 | 155265218 | E067 | -39886 |
| chr1 | 155265300 | 155265447 | E067 | -39657 |
| chr1 | 155265519 | 155265691 | E067 | -39413 |
| chr1 | 155278116 | 155279667 | E067 | -25437 |
| chr1 | 155291965 | 155295537 | E067 | -9567 |
| chr1 | 155264992 | 155265218 | E068 | -39886 |
| chr1 | 155278116 | 155279667 | E068 | -25437 |
| chr1 | 155291965 | 155295537 | E068 | -9567 |
| chr1 | 155264992 | 155265218 | E069 | -39886 |
| chr1 | 155265300 | 155265447 | E069 | -39657 |
| chr1 | 155265519 | 155265691 | E069 | -39413 |
| chr1 | 155278116 | 155279667 | E069 | -25437 |
| chr1 | 155291965 | 155295537 | E069 | -9567 |
| chr1 | 155278116 | 155279667 | E070 | -25437 |
| chr1 | 155291965 | 155295537 | E070 | -9567 |
| chr1 | 155278116 | 155279667 | E071 | -25437 |
| chr1 | 155291965 | 155295537 | E071 | -9567 |
| chr1 | 155264992 | 155265218 | E072 | -39886 |
| chr1 | 155265300 | 155265447 | E072 | -39657 |
| chr1 | 155277771 | 155278009 | E072 | -27095 |
| chr1 | 155278116 | 155279667 | E072 | -25437 |
| chr1 | 155291965 | 155295537 | E072 | -9567 |
| chr1 | 155277771 | 155278009 | E073 | -27095 |
| chr1 | 155278116 | 155279667 | E073 | -25437 |
| chr1 | 155291965 | 155295537 | E073 | -9567 |
| chr1 | 155278116 | 155279667 | E074 | -25437 |
| chr1 | 155291965 | 155295537 | E074 | -9567 |
| chr1 | 155278116 | 155279667 | E081 | -25437 |
| chr1 | 155278116 | 155279667 | E082 | -25437 |
| chr1 | 155291965 | 155295537 | E082 | -9567 |