rs1881942

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0475 (14243/29942,GnomAD)
C=0487 (2440/5008,1000G)
T==0491 (1893/3854,ALSPAC)
T==0482 (1787/3708,TWINSUK)
chr3:113133204 (GRCh38.p7) (3q13.2)
ND
GWASdb2
1   publication(s)
See rs on genome
51 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.113133204T>C
GRCh37.p13 chr 3NC_000003.11:g.112852051T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.725C=0.275
1000GenomesAmericanSub694T=0.610C=0.390
1000GenomesEast AsianSub1008T=0.269C=0.731
1000GenomesEuropeSub1006T=0.482C=0.518
1000GenomesGlobalStudy-wide5008T=0.513C=0.487
1000GenomesSouth AsianSub978T=0.440C=0.560
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.491C=0.509
The Genome Aggregation DatabaseAfricanSub8720T=0.718C=0.282
The Genome Aggregation DatabaseAmericanSub838T=0.680C=0.320
The Genome Aggregation DatabaseEast AsianSub1620T=0.267C=0.733
The Genome Aggregation DatabaseEuropeSub18462T=0.450C=0.549
The Genome Aggregation DatabaseGlobalStudy-wide29942T=0.524C=0.475
The Genome Aggregation DatabaseOtherSub302T=0.410C=0.590
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.482C=0.518
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs18819424.81E-05nicotine dependence17158188

eQTL of rs1881942 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr3:112852051RP11-572M11.3ENSG00000243795.1T>C1.7934e-9-34615Cerebellum
Chr3:112852051RP11-572M11.4ENSG00000240057.1T>C5.5463e-7113672Frontal_Cortex_BA9
Chr3:112852051RP11-572M11.4ENSG00000240057.1T>C3.2013e-8113672Hypothalamus
Chr3:112852051RP11-572M11.4ENSG00000240057.1T>C9.9039e-4113672Cerebellar_Hemisphere
Chr3:112852051RP11-572M11.4ENSG00000240057.1T>C7.6438e-11113672Caudate_basal_ganglia
Chr3:112852051RP11-572M11.4ENSG00000240057.1T>C2.3853e-8113672Hippocampus
Chr3:112852051RP11-572M11.4ENSG00000240057.1T>C1.3198e-9113672Substantia_nigra
Chr3:112852051RP11-572M11.4ENSG00000240057.1T>C2.5271e-7113672Putamen_basal_ganglia
Chr3:112852051RP11-572M11.4ENSG00000240057.1T>C1.1383e-10113672Nucleus_accumbens_basal_ganglia

meQTL of rs1881942 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3112885282112886383E06833231
chr3112886404112886517E06834353
chr3112886586112886904E06834535
chr3112885282112886383E06933231
chr3112805359112805737E070-46314
chr3112805757112805902E070-46149
chr3112805942112806037E070-46014
chr3112806052112806157E070-45894
chr3112823627112823829E070-28222
chr3112823851112824037E070-28014
chr3112824050112824180E070-27871
chr3112885282112886383E07033231
chr3112886404112886517E07034353
chr3112886586112886904E07034535
chr3112887022112887131E07034971
chr3112887133112887676E07035082
chr3112887710112887760E07035659
chr3112887912112888047E07035861
chr3112888117112888208E07036066
chr3112888226112888303E07036175
chr3112888478112888528E07036427
chr3112888778112889006E07036727
chr3112803392112803487E071-48564
chr3112885282112886383E07133231
chr3112888478112888528E07236427
chr3112888778112889006E07236727
chr3112889100112889150E07237049
chr3112885282112886383E07433231
chr3112888478112888528E07436427
chr3112888778112889006E07436727
chr3112889100112889150E07437049
chr3112805757112805902E081-46149
chr3112805942112806037E081-46014
chr3112806052112806157E081-45894
chr3112806276112806423E081-45628
chr3112806554112806833E081-45218
chr3112885282112886383E08133231
chr3112886404112886517E08134353
chr3112886586112886904E08134535
chr3112866346112867642E08214295
chr3112867742112868007E08215691
chr3112885282112886383E08233231
chr3112887022112887131E08234971
chr3112887133112887676E08235082
chr3112887710112887760E08235659
chr3112887912112888047E08235861
chr3112888117112888208E08236066
chr3112888226112888303E08236175
chr3112888478112888528E08236427
chr3112888778112889006E08236727
chr3112893230112893363E08241179