SNP Detail Info-rs1891224

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0044 (1342/29994,GnomAD)
G==0063 (1848/29118,TOPMED)
G==0094 (470/5008,1000G)
G==0009 (35/3854,ALSPAC)
G==0008 (30/3708,TWINSUK)

Position: chr1:119312119 (GRCh38.p7) (1p12)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 17 Enhancers around

Promoter: 9 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.119312119G>A
GRCh37.p13 chr 1	NC_000001.10:g.119854742G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.127	A=0.873
1000Genomes	American	Sub	694	G=0.020	A=0.980
1000Genomes	East Asian	Sub	1008	G=0.157	A=0.843
1000Genomes	Europe	Sub	1006	G=0.015	A=0.985
1000Genomes	Global	Study-wide	5008	G=0.094	A=0.906
1000Genomes	South Asian	Sub	978	G=0.120	A=0.880
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.009	A=0.991
The Genome Aggregation Database	African	Sub	8728	G=0.102	A=0.898
The Genome Aggregation Database	American	Sub	838	G=0.010	A=0.990
The Genome Aggregation Database	East Asian	Sub	1620	G=0.112	A=0.888
The Genome Aggregation Database	Europe	Sub	18506	G=0.013	A=0.986
The Genome Aggregation Database	Global	Study-wide	29994	G=0.044	A=0.955
The Genome Aggregation Database	Other	Sub	302	G=0.020	A=0.980
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.063	A=0.936
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.008	A=0.992

PMID	Title	Author	Journal
22096494	A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study.	Zuo L	PLoS One

SNP ID	p-value	Traits	Study
rs1891224	1.9E-06	alcohol dependence	22096494

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	119868870	119869562	E070	14128
chr1	119872303	119872476	E070	17561
chr1	119872525	119872715	E070	17783
chr1	119873739	119873850	E070	18997
chr1	119873922	119873989	E070	19180
chr1	119890560	119890680	E070	35818
chr1	119890743	119890831	E070	36001
chr1	119891029	119891079	E070	36287
chr1	119872303	119872476	E071	17561
chr1	119903829	119904359	E074	49087
chr1	119904383	119904433	E074	49641
chr1	119844224	119844284	E081	-10458
chr1	119844691	119844946	E081	-9796
chr1	119846351	119846404	E081	-8338
chr1	119846466	119846575	E081	-8167
chr1	119846595	119846751	E081	-7991
chr1	119846770	119846833	E081	-7909

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr1	119869604	119870819	E067	14862
chr1	119869604	119870819	E068	14862
chr1	119869604	119870819	E069	14862
chr1	119869604	119870819	E070	14862
chr1	119869604	119870819	E071	14862
chr1	119869604	119870819	E072	14862
chr1	119869604	119870819	E073	14862
chr1	119869604	119870819	E074	14862
chr1	119869604	119870819	E082	14862

rs1891224