rs1892409

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0197 (5902/29966,GnomAD)
T=0252 (7357/29118,TOPMED)
T=0230 (1153/5008,1000G)
T=0107 (414/3854,ALSPAC)
T=0119 (441/3708,TWINSUK)
chr1:117216703 (GRCh38.p7) (1p12)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.117216703C>T
GRCh37.p13 chr 1NC_000001.10:g.117759325C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.530T=0.470
1000GenomesAmericanSub694C=0.790T=0.210
1000GenomesEast AsianSub1008C=0.862T=0.138
1000GenomesEuropeSub1006C=0.870T=0.130
1000GenomesGlobalStudy-wide5008C=0.770T=0.230
1000GenomesSouth AsianSub978C=0.880T=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.893T=0.107
The Genome Aggregation DatabaseAfricanSub8708C=0.579T=0.421
The Genome Aggregation DatabaseAmericanSub838C=0.790T=0.210
The Genome Aggregation DatabaseEast AsianSub1616C=0.874T=0.126
The Genome Aggregation DatabaseEuropeSub18502C=0.901T=0.098
The Genome Aggregation DatabaseGlobalStudy-wide29966C=0.803T=0.197
The Genome Aggregation DatabaseOtherSub302C=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.747T=0.252
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.881T=0.119
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs18924090.000559alcohol dependence20201924

eQTL of rs1892409 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1892409 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1117714306117715174E068-44151
chr1117774413117774453E06815088
chr1117774568117774950E06815243
chr1117714306117715174E069-44151
chr1117719132117719313E069-40012
chr1117719356117719460E069-39865
chr1117714306117715174E070-44151
chr1117714306117715174E071-44151
chr1117774413117774453E07115088
chr1117774568117774950E07115243
chr1117780443117780603E07121118
chr1117780771117780883E07121446
chr1117714306117715174E072-44151
chr1117722923117723005E074-36320
chr1117723124117723376E074-35949
chr1117714306117715174E081-44151
chr1117724975117725335E081-33990
chr1117714306117715174E082-44151
chr1117722923117723005E082-36320
chr1117723124117723376E082-35949
chr1117724116117724645E082-34680