SNP Detail Info-rs1894709

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.175163235G>T
GRCh37.p13 chr 1	NC_000001.10:g.175132371G>T

Molecule type	Change	Amino acid[Codon]	SO Term
KIAA0040 transcript variant 1	NM_001162893.1:c.	N/A	Intron Variant
KIAA0040 transcript variant 3	NM_001162894.1:c.	N/A	Intron Variant
KIAA0040 transcript variant 4	NM_001162895.1:c.	N/A	Intron Variant
KIAA0040 transcript variant 5	NM_001319230.1:c.	N/A	Intron Variant
KIAA0040 transcript variant 6	NM_001319231.1:c.	N/A	Intron Variant
KIAA0040 transcript variant 2	NM_014656.2:c.	N/A	Intron Variant
KIAA0040 transcript variant X1	XM_017002909.1:c.	N/A	Intron Variant
KIAA0040 transcript variant X2	XM_017002910.1:c.	N/A	Intron Variant
KIAA0040 transcript variant X3	XM_017002911.1:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.625	T=0.375
1000Genomes	American	Sub	694	G=0.680	T=0.320
1000Genomes	East Asian	Sub	1008	G=0.856	T=0.144
1000Genomes	Europe	Sub	1006	G=0.561	T=0.439
1000Genomes	Global	Study-wide	5008	G=0.685	T=0.315
1000Genomes	South Asian	Sub	978	G=0.720	T=0.280
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.535	T=0.465
The Genome Aggregation Database	African	Sub	8690	G=0.602	T=0.398
The Genome Aggregation Database	American	Sub	836	G=0.710	T=0.290
The Genome Aggregation Database	East Asian	Sub	1612	G=0.870	T=0.130
The Genome Aggregation Database	Europe	Sub	18470	G=0.536	T=0.463
The Genome Aggregation Database	Global	Study-wide	29910	G=0.580	T=0.419
The Genome Aggregation Database	Other	Sub	302	G=0.730	T=0.270
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.605	T=0.394
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.521	T=0.479

PMID	Title	Author	Journal
21703634	A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.	Wang KS	J Psychiatr Res
21956439	Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.	Zuo L	Neuropsychopharmacology
20202923	A genome-wide association study of alcohol dependence.	Bierut LJ	Proc Natl Acad Sci U S A
22488850	Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.	Zuo L	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs1894709	0.0000016	alcohol and nictotine co-dependence	22488850
rs1894709	0.00000212	alcohol dependence	21703634
rs1894709	0.00000278	alcohol dependence	20202923
rs1894709	0.00043	alcohol dependence	21956439

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	175127262	175127638	E067	-4733
chr1	175127726	175127793	E067	-4578
chr1	175121212	175121706	E069	-10665
chr1	175138495	175138718	E069	6124
chr1	175117508	175117593	E070	-14778
chr1	175131566	175131616	E070	-755
chr1	175131702	175131793	E070	-578
chr1	175131845	175132044	E070	-327
chr1	175132208	175132358	E070	-13
chr1	175169465	175169525	E071	37094
chr1	175169774	175170871	E071	37403
chr1	175121212	175121706	E072	-10665
chr1	175173548	175173704	E073	41177
chr1	175173714	175173889	E073	41343
chr1	175115170	175115364	E081	-17007
chr1	175115429	175115500	E081	-16871
chr1	175115737	175116333	E081	-16038
chr1	175116438	175116534	E081	-15837
chr1	175116763	175117071	E081	-15300
chr1	175117325	175117401	E081	-14970
chr1	175117508	175117593	E081	-14778
chr1	175120951	175121040	E081	-11331
chr1	175121212	175121706	E081	-10665
chr1	175127262	175127638	E082	-4733
chr1	175127726	175127793	E082	-4578
chr1	175173548	175173704	E082	41177
chr1	175173714	175173889	E082	41343

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr1	175160861	175163201	E067	28490
chr1	175160861	175163201	E068	28490
chr1	175160861	175163201	E069	28490
chr1	175160861	175163201	E071	28490
chr1	175160861	175163201	E072	28490
chr1	175160861	175163201	E073	28490
chr1	175160861	175163201	E074	28490
chr1	175160861	175163201	E082	28490

rs1894709