rs1909749

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0257 (7693/29906,GnomAD)
T=0176 (883/5008,1000G)
T=0345 (1330/3854,ALSPAC)
T=0351 (1300/3708,TWINSUK)
chr16:56578790 (GRCh38.p7) (16q13)
AD
GWASdb2
2   publication(s)
See rs on genome
224 Enhancers around
66 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.56578790C>T
GRCh37.p13 chr 16NC_000016.9:g.56612702C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.899T=0.101
1000GenomesAmericanSub694C=0.820T=0.180
1000GenomesEast AsianSub1008C=0.920T=0.080
1000GenomesEuropeSub1006C=0.641T=0.359
1000GenomesGlobalStudy-wide5008C=0.824T=0.176
1000GenomesSouth AsianSub978C=0.820T=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.655T=0.345
The Genome Aggregation DatabaseAfricanSub8710C=0.862T=0.138
The Genome Aggregation DatabaseAmericanSub832C=0.790T=0.210
The Genome Aggregation DatabaseEast AsianSub1618C=0.920T=0.080
The Genome Aggregation DatabaseEuropeSub18444C=0.669T=0.331
The Genome Aggregation DatabaseGlobalStudy-wide29906C=0.742T=0.257
The Genome Aggregation DatabaseOtherSub302C=0.730T=0.270
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.649T=0.351
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res
26529669Genetic variation in metallothionein and metal-regulatory transcription factor 1 in relation to urinary cadmium, copper, and zinc.Adams SVToxicol Appl Pharmacol

P-Value

SNP ID p-value Traits Study
rs19097490.000825alcohol dependence21314694

eQTL of rs1909749 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1909749 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr165657365156574475E067-38227
chr165658035656580456E067-32246
chr165658078456580838E067-31864
chr165658098956582019E067-30683
chr165658206056582468E067-30234
chr165658277956582896E067-29806
chr165658292356582988E067-29714
chr165658304856583409E067-29293
chr165658356456583624E067-29078
chr165658372956584142E067-28560
chr165658458156584695E067-28007
chr165658474856584798E067-27904
chr165658486456584909E067-27793
chr165658495456585080E067-27622
chr165658555556585599E067-27103
chr165658566356585739E067-26963
chr165658574156586239E067-26463
chr165658633156586553E067-26149
chr165659134756591466E067-21236
chr165659169256591865E067-20837
chr165659228956592669E067-20033
chr165663416056634705E06721458
chr165663474456634848E06722042
chr165663493956634989E06722237
chr165665743956657495E06744737
chr165665756456657604E06744862
chr165665769556657810E06744993
chr165665789556658011E06745193
chr165665807156658130E06745369
chr165665815056658200E06745448
chr165665822456658304E06745522
chr165665835156658391E06745649
chr165665853556658595E06745833
chr165657365156574475E068-38227
chr165658035656580456E068-32246
chr165658206056582468E068-30234
chr165658277956582896E068-29806
chr165658292356582988E068-29714
chr165658304856583409E068-29293
chr165658356456583624E068-29078
chr165658372956584142E068-28560
chr165658458156584695E068-28007
chr165658474856584798E068-27904
chr165658486456584909E068-27793
chr165658495456585080E068-27622
chr165658555556585599E068-27103
chr165658566356585739E068-26963
chr165658574156586239E068-26463
chr165658633156586553E068-26149
chr165659134756591466E068-21236
chr165659169256591865E068-20837
chr165659228956592669E068-20033
chr165662544556625653E06812743
chr165662568356625994E06812981
chr165663416056634705E06821458
chr165663474456634848E06822042
chr165664526856645909E06832566
chr165665219156652503E06839489
chr165658035656580456E069-32246
chr165658078456580838E069-31864
chr165658206056582468E069-30234
chr165658277956582896E069-29806
chr165658292356582988E069-29714
chr165658304856583409E069-29293
chr165658356456583624E069-29078
chr165658372956584142E069-28560
chr165658458156584695E069-28007
chr165658474856584798E069-27904
chr165658486456584909E069-27793
chr165658495456585080E069-27622
chr165658555556585599E069-27103
chr165658566356585739E069-26963
chr165658574156586239E069-26463
chr165658633156586553E069-26149
chr165658737756587471E069-25231
chr165659134756591466E069-21236
chr165659169256591865E069-20837
chr165659228956592669E069-20033
chr165662544556625653E06912743
chr165663416056634705E06921458
chr165663474456634848E06922042
chr165663493956634989E06922237
chr165663532156635599E06922619
chr165664526856645909E06932566
chr165658098956582019E070-30683
chr165658206056582468E070-30234
chr165658277956582896E070-29806
chr165658292356582988E070-29714
chr165658574156586239E070-26463
chr165658633156586553E070-26149
chr165659134756591466E070-21236
chr165659169256591865E070-20837
chr165657365156574475E071-38227
chr165658035656580456E071-32246
chr165658078456580838E071-31864
chr165658098956582019E071-30683
chr165658206056582468E071-30234
chr165658277956582896E071-29806
chr165658292356582988E071-29714
chr165658304856583409E071-29293
chr165658356456583624E071-29078
chr165658372956584142E071-28560
chr165658458156584695E071-28007
chr165658474856584798E071-27904
chr165658486456584909E071-27793
chr165658495456585080E071-27622
chr165658555556585599E071-27103
chr165658566356585739E071-26963
chr165658574156586239E071-26463
chr165658633156586553E071-26149
chr165658737756587471E071-25231
chr165659134756591466E071-21236
chr165659169256591865E071-20837
chr165659228956592669E071-20033
chr165662544556625653E07112743
chr165663416056634705E07121458
chr165663474456634848E07122042
chr165663493956634989E07122237
chr165663532156635599E07122619
chr165663875056638940E07126048
chr165663900156639160E07126299
chr165663918756639482E07126485
chr165663952556639675E07126823
chr165664526856645909E07132566
chr165665219156652503E07139489
chr165665743956657495E07144737
chr165665756456657604E07144862
chr165665769556657810E07144993
chr165665789556658011E07145193
chr165665807156658130E07145369
chr165665815056658200E07145448
chr165665822456658304E07145522
chr165665835156658391E07145649
chr165665853556658595E07145833
chr165657365156574475E072-38227
chr165657829656578408E072-34294
chr165657851556578572E072-34130
chr165657889356578943E072-33759
chr165658035656580456E072-32246
chr165658206056582468E072-30234
chr165658277956582896E072-29806
chr165658292356582988E072-29714
chr165658304856583409E072-29293
chr165658356456583624E072-29078
chr165658372956584142E072-28560
chr165658458156584695E072-28007
chr165658474856584798E072-27904
chr165658486456584909E072-27793
chr165658495456585080E072-27622
chr165658555556585599E072-27103
chr165658566356585739E072-26963
chr165658574156586239E072-26463
chr165658633156586553E072-26149
chr165658737756587471E072-25231
chr165658934856589399E072-23303
chr165659134756591466E072-21236
chr165659169256591865E072-20837
chr165659228956592669E072-20033
chr165663416056634705E07221458
chr165663474456634848E07222042
chr165664526856645909E07232566
chr165657365156574475E073-38227
chr165658098956582019E073-30683
chr165658206056582468E073-30234
chr165658277956582896E073-29806
chr165658292356582988E073-29714
chr165658304856583409E073-29293
chr165658356456583624E073-29078
chr165658372956584142E073-28560
chr165658458156584695E073-28007
chr165658474856584798E073-27904
chr165658486456584909E073-27793
chr165658495456585080E073-27622
chr165658555556585599E073-27103
chr165658566356585739E073-26963
chr165658574156586239E073-26463
chr165658633156586553E073-26149
chr165659134756591466E073-21236
chr165659169256591865E073-20837
chr165659228956592669E073-20033
chr165662544556625653E07312743
chr165663753856637963E07324836
chr165663799956638055E07325297
chr165664526856645909E07332566
chr165657365156574475E074-38227
chr165658035656580456E074-32246
chr165658098956582019E074-30683
chr165658206056582468E074-30234
chr165658277956582896E074-29806
chr165658292356582988E074-29714
chr165658304856583409E074-29293
chr165658356456583624E074-29078
chr165658372956584142E074-28560
chr165658458156584695E074-28007
chr165658474856584798E074-27904
chr165658486456584909E074-27793
chr165658495456585080E074-27622
chr165658555556585599E074-27103
chr165658566356585739E074-26963
chr165658574156586239E074-26463
chr165658633156586553E074-26149
chr165658737756587471E074-25231
chr165659134756591466E074-21236
chr165659169256591865E074-20837
chr165659228956592669E074-20033
chr165662544556625653E07412743
chr165662568356625994E07412981
chr165663474456634848E07422042
chr165663753856637963E07424836
chr165663799956638055E07425297
chr165664526856645909E07432566
chr165659228956592669E081-20033
chr165661559656615640E0812894
chr165661564856615713E0812946
chr165661577656615858E0813074
chr165661597256616265E0813270
chr165661631556616451E0813613
chr165661660556616679E0813903
chr165658098956582019E082-30683
chr165658574156586239E082-26463
chr165658633156586553E082-26149
chr165659169256591865E082-20837
chr165659228956592669E082-20033
chr165665219156652503E08239489










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr165662289256623879E06710190
chr165662420356624253E06711501
chr165662428456624334E06711582
chr165662447956624541E06711777
chr165665878356658919E06746081
chr165665894856660225E06746246
chr165666030156660407E06747599
chr165666046356660518E06747761
chr165666054756661682E06747845
chr165662289256623879E06810190
chr165662420356624253E06811501
chr165662428456624334E06811582
chr165665878356658919E06846081
chr165665894856660225E06846246
chr165666030156660407E06847599
chr165666046356660518E06847761
chr165666054756661682E06847845
chr165662269156622751E0699989
chr165662289256623879E06910190
chr165662420356624253E06911501
chr165662428456624334E06911582
chr165662447956624541E06911777
chr165665878356658919E06946081
chr165665894856660225E06946246
chr165666030156660407E06947599
chr165666046356660518E06947761
chr165666054756661682E06947845
chr165662289256623879E07010190
chr165662420356624253E07011501
chr165662428456624334E07011582
chr165662447956624541E07011777
chr165662289256623879E07110190
chr165662420356624253E07111501
chr165662428456624334E07111582
chr165662447956624541E07111777
chr165665878356658919E07146081
chr165665894856660225E07146246
chr165666030156660407E07147599
chr165666046356660518E07147761
chr165666054756661682E07147845
chr165662289256623879E07210190
chr165662420356624253E07211501
chr165662428456624334E07211582
chr165662447956624541E07211777
chr165665878356658919E07246081
chr165665894856660225E07246246
chr165666030156660407E07247599
chr165666046356660518E07247761
chr165666054756661682E07247845
chr165662289256623879E07310190
chr165662420356624253E07311501
chr165662428456624334E07311582
chr165662447956624541E07311777
chr165665894856660225E07346246
chr165666030156660407E07347599
chr165666046356660518E07347761
chr165666054756661682E07347845
chr165662289256623879E07410190
chr165665878356658919E07446081
chr165665894856660225E07446246
chr165666030156660407E07447599
chr165666046356660518E07447761
chr165666054756661682E07447845
chr165662269156622751E0829989
chr165662289256623879E08210190
chr165665894856660225E08246246