SNP Detail Info-rs1910370

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0397 (11898/29912,GnomAD)
A=0389 (11333/29116,TOPMED)
A=0317 (1587/5008,1000G)
A=0465 (1792/3854,ALSPAC)
A=0490 (1816/3708,TWINSUK)

Position: chr2:67867965 (GRCh38.p7) (2p14)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 39 Enhancers around

Promoter: 1 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.67867965G>A
GRCh37.p13 chr 2	NC_000002.11:g.68095097G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.777	A=0.223
1000Genomes	American	Sub	694	G=0.590	A=0.410
1000Genomes	East Asian	Sub	1008	G=0.776	A=0.224
1000Genomes	Europe	Sub	1006	G=0.509	A=0.491
1000Genomes	Global	Study-wide	5008	G=0.683	A=0.317
1000Genomes	South Asian	Sub	978	G=0.710	A=0.290
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.535	A=0.465
The Genome Aggregation Database	African	Sub	8714	G=0.744	A=0.256
The Genome Aggregation Database	American	Sub	838	G=0.570	A=0.430
The Genome Aggregation Database	East Asian	Sub	1610	G=0.786	A=0.214
The Genome Aggregation Database	Europe	Sub	18450	G=0.521	A=0.478
The Genome Aggregation Database	Global	Study-wide	29912	G=0.602	A=0.397
The Genome Aggregation Database	Other	Sub	300	G=0.570	A=0.430
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.610	A=0.389
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.510	A=0.490

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs1910370	0.000778	alcohol consumption (maxi-drinks)	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	68073151	68073975	E067	-21122
chr2	68075765	68075965	E067	-19132
chr2	68076143	68076196	E067	-18901
chr2	68075765	68075965	E068	-19132
chr2	68076143	68076196	E068	-18901
chr2	68076711	68076770	E068	-18327
chr2	68106966	68108129	E068	11869
chr2	68075765	68075965	E069	-19132
chr2	68076143	68076196	E069	-18901
chr2	68051451	68051652	E070	-43445
chr2	68052261	68052332	E070	-42765
chr2	68052656	68052948	E070	-42149
chr2	68052978	68053065	E070	-42032
chr2	68053307	68053352	E070	-41745
chr2	68072792	68073087	E070	-22010
chr2	68073151	68073975	E070	-21122
chr2	68076143	68076196	E070	-18901
chr2	68104522	68104780	E070	9425
chr2	68105075	68105153	E070	9978
chr2	68106857	68106925	E070	11760
chr2	68106966	68108129	E070	11869
chr2	68075765	68075965	E071	-19132
chr2	68076143	68076196	E071	-18901
chr2	68075765	68075965	E072	-19132
chr2	68076143	68076196	E072	-18901
chr2	68075765	68075965	E073	-19132
chr2	68076143	68076196	E073	-18901
chr2	68073151	68073975	E074	-21122
chr2	68075765	68075965	E074	-19132
chr2	68076143	68076196	E074	-18901
chr2	68051451	68051652	E081	-43445
chr2	68052978	68053065	E081	-42032
chr2	68079172	68079694	E081	-15403
chr2	68079710	68079801	E081	-15296
chr2	68095248	68095401	E081	151
chr2	68095442	68095700	E081	345
chr2	68104522	68104780	E081	9425
chr2	68104522	68104780	E082	9425
chr2	68105075	68105153	E082	9978

rs1910370