rs1911588

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0286 (8580/29934,GnomAD)
C=0236 (6891/29118,TOPMED)
C=0272 (1361/5008,1000G)
C=0374 (1442/3854,ALSPAC)
C=0371 (1377/3708,TWINSUK)
chr4:147099992 (GRCh38.p7) (4q31.22)
AD
GWASdb2
1   publication(s)
See rs on genome
15 Enhancers around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.147099992T>C
GRCh37.p13 chr 4NC_000004.11:g.148021144T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.921C=0.079
1000GenomesAmericanSub694T=0.730C=0.270
1000GenomesEast AsianSub1008T=0.711C=0.289
1000GenomesEuropeSub1006T=0.638C=0.362
1000GenomesGlobalStudy-wide5008T=0.728C=0.272
1000GenomesSouth AsianSub978T=0.580C=0.420
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.626C=0.374
The Genome Aggregation DatabaseAfricanSub8714T=0.887C=0.113
The Genome Aggregation DatabaseAmericanSub836T=0.750C=0.250
The Genome Aggregation DatabaseEast AsianSub1620T=0.674C=0.326
The Genome Aggregation DatabaseEuropeSub18462T=0.634C=0.366
The Genome Aggregation DatabaseGlobalStudy-wide29934T=0.713C=0.286
The Genome Aggregation DatabaseOtherSub302T=0.690C=0.310
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.763C=0.236
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.629C=0.371
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs19115880.00097alcohol dependence20201924

eQTL of rs1911588 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1911588 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4148000922148001003E068-20141
chr4148024528148025132E0693384
chr4148000258148000801E070-20343
chr4148000922148001003E070-20141
chr4148001435148001662E070-19482
chr4148001667148001759E070-19385
chr4148000922148001003E071-20141
chr4148001435148001662E071-19482
chr4147981263147982211E074-38933
chr4147982326147982416E074-38728
chr4147982478147982528E074-38616
chr4148000258148000801E081-20343
chr4148000922148001003E081-20141
chr4148000258148000801E082-20343
chr4148000922148001003E082-20141







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr4147978179147978477E067-42667
chr4147978487147979229E067-41915
chr4147978487147979229E068-41915
chr4147978487147979229E069-41915
chr4147978487147979229E071-41915
chr4147978487147979229E072-41915
chr4147978487147979229E074-41915