rs1913586

Homo sapiens
T>A / T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0342 (10225/29876,GnomAD)
T==0290 (8466/29118,TOPMED)
T==0316 (1585/5008,1000G)
T==0425 (1637/3854,ALSPAC)
T==0417 (1545/3708,TWINSUK)
chr4:107534064 (GRCh38.p7) (4q25)
AD
GWASdb2
1   publication(s)
See rs on genome
235 Enhancers around
53 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.107534064T>A
GRCh38.p7 chr 4NC_000004.12:g.107534064T>C
GRCh37.p13 chr 4NC_000004.11:g.108455221T>A
GRCh37.p13 chr 4NC_000004.11:g.108455221T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.078C=0.922
1000GenomesAmericanSub694T=0.270C=0.730
1000GenomesEast AsianSub1008T=0.444C=0.556
1000GenomesEuropeSub1006T=0.424C=0.576
1000GenomesGlobalStudy-wide5008T=0.316C=0.684
1000GenomesSouth AsianSub978T=0.430C=0.570
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.425C=0.575
The Genome Aggregation DatabaseAfricanSub8718T=0.127A=0.000
The Genome Aggregation DatabaseAmericanSub838T=0.270A=0.00,
The Genome Aggregation DatabaseEast AsianSub1584T=0.443A=0.000
The Genome Aggregation DatabaseEuropeSub18434T=0.437A=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29876T=0.342A=0.000
The Genome Aggregation DatabaseOtherSub302T=0.410A=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.290C=0.709
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.417C=0.583
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs19135860.000543alcohol dependence21314694

eQTL of rs1913586 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1913586 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr479311517931241E067-43593
chr479313007931768E067-43066
chr479579297958432E067-16402
chr479584957958689E067-16145
chr479621577963073E067-11761
chr479649947965054E067-9780
chr479655147965588E067-9246
chr479686457969176E067-5658
chr479693157969391E067-5443
chr479695527970349E067-4485
chr479711067972347E067-2487
chr479723657972538E067-2296
chr479726637972763E067-2071
chr479728487972941E067-1893
chr479729847973070E067-1764
chr479736997973841E067-993
chr479738987973978E067-856
chr479740227975009E0670
chr479752747975695E067440
chr480116398012070E06736805
chr480123018013082E06737467
chr480208038020857E06745969
chr479308257930875E068-43959
chr479309627931096E068-43738
chr479311517931241E068-43593
chr479313007931768E068-43066
chr479319587932056E068-42778
chr479579297958432E068-16402
chr479584957958689E068-16145
chr479621577963073E068-11761
chr479649947965054E068-9780
chr479655147965588E068-9246
chr479711067972347E068-2487
chr479723657972538E068-2296
chr479752747975695E068440
chr479781437978462E0683309
chr479784907978550E0683656
chr480170028017106E06842168
chr480173018017385E06842467
chr480173868017543E06842552
chr480208038020857E06845969
chr480222158022294E06847381
chr479308257930875E069-43959
chr479309627931096E069-43738
chr479387057938764E069-36070
chr479579297958432E069-16402
chr479584957958689E069-16145
chr479616757961818E069-13016
chr479618977961998E069-12836
chr479621577963073E069-11761
chr479649947965054E069-9780
chr479655147965588E069-9246
chr479656337965841E069-8993
chr479686457969176E069-5658
chr479693157969391E069-5443
chr479695527970349E069-4485
chr479703547970480E069-4354
chr479711067972347E069-2487
chr479723657972538E069-2296
chr479726637972763E069-2071
chr479728487972941E069-1893
chr479729847973070E069-1764
chr479731607973214E069-1620
chr479736997973841E069-993
chr479752747975695E069440
chr480116398012070E06936805
chr480123018013082E06937467
chr480131918013273E06938357
chr480170028017106E06942168
chr480173018017385E06942467
chr480205638020653E06945729
chr480208038020857E06945969
chr479289557929062E070-45772
chr479298787929947E070-44887
chr479309627931096E070-43738
chr479311517931241E070-43593
chr479313007931768E070-43066
chr479319587932056E070-42778
chr479609637961265E070-13569
chr479616757961818E070-13016
chr479618977961998E070-12836
chr479621577963073E070-11761
chr479633127963372E070-11462
chr479644907964564E070-10270
chr479711067972347E070-2487
chr479723657972538E070-2296
chr479942137994276E07019379
chr479945297994613E07019695
chr480108128010876E07035978
chr480205638020653E07045729
chr480208038020857E07045969
chr480222158022294E07047381
chr479259077926178E071-48656
chr479308257930875E071-43959
chr479309627931096E071-43738
chr479311517931241E071-43593
chr479313007931768E071-43066
chr479579297958432E071-16402
chr479584957958689E071-16145
chr479621577963073E071-11761
chr479644907964564E071-10270
chr479649947965054E071-9780
chr479655147965588E071-9246
chr479695527970349E071-4485
chr479703547970480E071-4354
chr479711067972347E071-2487
chr479723657972538E071-2296
chr479740227975009E0710
chr479752747975695E071440
chr480123018013082E07137467
chr480131918013273E07138357
chr480170028017106E07142168
chr480173868017543E07142552
chr480205638020653E07145729
chr480208038020857E07145969
chr480222158022294E07147381
chr479263987926691E072-48143
chr479311517931241E072-43593
chr479313007931768E072-43066
chr479579297958432E072-16402
chr479584957958689E072-16145
chr479621577963073E072-11761
chr479649947965054E072-9780
chr479655147965588E072-9246
chr479656337965841E072-8993
chr479686457969176E072-5658
chr479693157969391E072-5443
chr479695527970349E072-4485
chr479703547970480E072-4354
chr479711067972347E072-2487
chr479723657972538E072-2296
chr479726637972763E072-2071
chr479728487972941E072-1893
chr479729847973070E072-1764
chr479736997973841E072-993
chr479738987973978E072-856
chr479740227975009E0720
chr479752747975695E072440
chr480116398012070E07236805
chr480123018013082E07237467
chr480131918013273E07238357
chr480205638020653E07245729
chr480208038020857E07245969
chr479263987926691E073-48143
chr479308257930875E073-43959
chr479309627931096E073-43738
chr479311517931241E073-43593
chr479313007931768E073-43066
chr479319587932056E073-42778
chr479616757961818E073-13016
chr479618977961998E073-12836
chr479621577963073E073-11761
chr479649947965054E073-9780
chr479655147965588E073-9246
chr479695527970349E073-4485
chr479703547970480E073-4354
chr479711067972347E073-2487
chr479723657972538E073-2296
chr479726637972763E073-2071
chr479728487972941E073-1893
chr479729847973070E073-1764
chr479731607973214E073-1620
chr479733287973449E073-1385
chr479736997973841E073-993
chr479738987973978E073-856
chr479740227975009E0730
chr479752747975695E073440
chr479878057988162E07312971
chr480116398012070E07336805
chr480123018013082E07337467
chr480131918013273E07338357
chr479309627931096E074-43738
chr479311517931241E074-43593
chr479313007931768E074-43066
chr479571357957455E074-17379
chr479579297958432E074-16402
chr479584957958689E074-16145
chr479649947965054E074-9780
chr479686457969176E074-5658
chr479693157969391E074-5443
chr479695527970349E074-4485
chr479711067972347E074-2487
chr479740227975009E0740
chr479752747975695E074440
chr480116398012070E07436805
chr480123018013082E07437467
chr480131918013273E07438357
chr480205638020653E07445729
chr480208038020857E07445969
chr479259077926178E081-48656
chr479263987926691E081-48143
chr479355437935700E081-39134
chr479357127935839E081-38995
chr479359837936110E081-38724
chr479387057938764E081-36070
chr479387697938836E081-35998
chr479389547939049E081-35785
chr479477867948088E081-26746
chr479482647948406E081-26428
chr479497667949925E081-24909
chr479501697950233E081-24601
chr479504557951283E081-23551
chr479515087951726E081-23108
chr479621577963073E081-11761
chr479695527970349E081-4485
chr479711067972347E081-2487
chr479723657972538E081-2296
chr479726637972763E081-2071
chr479728487972941E081-1893
chr479729847973070E081-1764
chr479731607973214E081-1620
chr479733287973449E081-1385
chr479781437978462E0813309
chr479784907978550E0813656
chr480116398012070E08136805
chr480123018013082E08137467
chr480131918013273E08138357
chr479263987926691E082-48143
chr479308257930875E082-43959
chr479309627931096E082-43738
chr479311517931241E082-43593
chr479355437935700E082-39134
chr479357127935839E082-38995
chr479359837936110E082-38724
chr479367297936779E082-38055
chr479373527937447E082-37387
chr479374757937535E082-37299
chr479377827937832E082-37002
chr479379207937970E082-36864
chr479477867948088E082-26746
chr479482647948406E082-26428
chr479504557951283E082-23551
chr479711067972347E082-2487
chr480116398012070E08236805
chr480123018013082E08237467










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr479395607940647E067-34187
chr479406567941194E067-33640
chr479412557942048E067-32786
chr480210258021150E06746191
chr480212298021419E06746395
chr480214518021629E06746617
chr480217138022059E06746879
chr479395607940647E068-34187
chr479406567941194E068-33640
chr479412557942048E068-32786
chr480212298021419E06846395
chr480214518021629E06846617
chr480217138022059E06846879
chr479395607940647E069-34187
chr479406567941194E069-33640
chr479412557942048E069-32786
chr480210258021150E06946191
chr480212298021419E06946395
chr480214518021629E06946617
chr480217138022059E06946879
chr479395607940647E070-34187
chr479406567941194E070-33640
chr479412557942048E070-32786
chr480210258021150E07046191
chr479395607940647E071-34187
chr479406567941194E071-33640
chr479412557942048E071-32786
chr480212298021419E07146395
chr480214518021629E07146617
chr480217138022059E07146879
chr479395607940647E072-34187
chr479406567941194E072-33640
chr479412557942048E072-32786
chr480210258021150E07246191
chr480212298021419E07246395
chr480214518021629E07246617
chr480217138022059E07246879
chr479395607940647E073-34187
chr479406567941194E073-33640
chr479412557942048E073-32786
chr480212298021419E07346395
chr480214518021629E07346617
chr479395607940647E074-34187
chr479406567941194E074-33640
chr479412557942048E074-32786
chr480210258021150E07446191
chr480212298021419E07446395
chr480214518021629E07446617
chr480217138022059E07446879
chr479395607940647E081-34187
chr479395607940647E082-34187
chr479406567941194E082-33640
chr479412557942048E082-32786