rs1922910

Homo sapiens
A>G
FGF12 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0229 (6862/29928,GnomAD)
A==0199 (5797/29118,TOPMED)
A==0209 (1049/5008,1000G)
A==0306 (1180/3854,ALSPAC)
A==0291 (1078/3708,TWINSUK)
chr3:192621072 (GRCh38.p7) (3q29)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.192621072A>G
GRCh37.p13 chr 3NC_000003.11:g.192338861A>G

Gene: FGF12, fibroblast growth factor 12(minus strand)

Molecule type Change Amino acid[Codon] SO Term
FGF12 transcript variant 2NM_004113.5:c.N/AIntron Variant
FGF12 transcript variant 1NM_021032.4:c.N/AGenic Upstream Transcript Variant
FGF12 transcript variant X3XM_017005879.1:c.N/AIntron Variant
FGF12 transcript variant X1XM_005247227.2:c.N/AGenic Upstream Transcript Variant
FGF12 transcript variant X2XM_006713538.3:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.014G=0.986
1000GenomesAmericanSub694A=0.220G=0.780
1000GenomesEast AsianSub1008A=0.245G=0.755
1000GenomesEuropeSub1006A=0.326G=0.674
1000GenomesGlobalStudy-wide5008A=0.209G=0.791
1000GenomesSouth AsianSub978A=0.310G=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.306G=0.694
The Genome Aggregation DatabaseAfricanSub8732A=0.058G=0.942
The Genome Aggregation DatabaseAmericanSub836A=0.270G=0.730
The Genome Aggregation DatabaseEast AsianSub1596A=0.253G=0.747
The Genome Aggregation DatabaseEuropeSub18462A=0.304G=0.695
The Genome Aggregation DatabaseGlobalStudy-wide29928A=0.229G=0.770
The Genome Aggregation DatabaseOtherSub302A=0.330G=0.670
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.199G=0.800
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.291G=0.709
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs19229108.18E-05alcohol withdrawal symptoms22072270

eQTL of rs1922910 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1922910 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3192326940192327344E067-11517
chr3192295684192295734E081-43127
chr3192295776192295911E081-42950
chr3192326940192327344E081-11517
chr3192338138192338362E081-499


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3192288886192289669E067-49192
chr3192288886192289669E068-49192
chr3192288886192289669E069-49192
chr3192288886192289669E070-49192
chr3192288886192289669E071-49192
chr3192288886192289669E072-49192
chr3192288886192289669E073-49192
chr3192288886192289669E074-49192
chr3192288886192289669E082-49192