SNP Detail Info-rs192590503

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

NKAIN2 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0023 (692/29968,GnomAD)
A=0020 (593/29118,TOPMED)
A=0006 (32/5008,1000G)
A=0025 (96/3854,ALSPAC)
A=0022 (82/3708,TWINSUK)

Position: chr6:124215869 (GRCh38.p7) (6q22.31)

Phenotype: OD

Dataset:

GWASCatalog

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 31 Enhancers around

Promoter: 0 Promoter around

Molecule type	Change	Amino acid[Codon]	SO Term
NKAIN2 transcript variant 1	NM_001040214.2:c.	N/A	Intron Variant
NKAIN2 transcript variant 3	NM_001300737.1:c.	N/A	Intron Variant
NKAIN2 transcript variant 4	NM_001300738.1:c.	N/A	Intron Variant
NKAIN2 transcript variant 5	NM_001300740.1:c.	N/A	Intron Variant
NKAIN2 transcript variant 2	NM_153355.4:c.	N/A	Intron Variant
NKAIN2 transcript variant X1	XM_011535501.2:c.	N/A	Intron Variant
NKAIN2 transcript variant X2	XM_011535502.2:c.	N/A	Intron Variant
NKAIN2 transcript variant X3	XM_011535503.2:c.	N/A	Intron Variant
NKAIN2 transcript variant X4	XM_017010318.1:c.	N/A	Intron Variant
NKAIN2 transcript variant X5	XM_017010319.1:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=1.000	A=0.000
1000Genomes	American	Sub	694	G=0.980	A=0.020
1000Genomes	East Asian	Sub	1008	G=1.000	A=0.000
1000Genomes	Europe	Sub	1006	G=0.985	A=0.015
1000Genomes	Global	Study-wide	5008	G=0.994	A=0.006
1000Genomes	South Asian	Sub	978	G=1.000	A=0.000
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.975	A=0.025
The Genome Aggregation Database	African	Sub	8724	G=0.996	A=0.004
The Genome Aggregation Database	American	Sub	838	G=0.990	A=0.010
The Genome Aggregation Database	East Asian	Sub	1622	G=1.000	A=0.000
The Genome Aggregation Database	Europe	Sub	18482	G=0.965	A=0.034
The Genome Aggregation Database	Global	Study-wide	29968	G=0.976	A=0.023
The Genome Aggregation Database	Other	Sub	302	G=0.970	A=0.030
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.979	A=0.020
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.978	A=0.022

PMID	Title	Author	Journal
29478698	Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.	Cheng Z	Biol Psychiatry

SNP ID	p-value	Traits	Study
rs192590503	3E-07	Opioid dependence	29478698

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr6	124521275	124521397	E070	-15617
chr6	124521456	124521599	E070	-15415
chr6	124521796	124522255	E070	-14759
chr6	124522294	124522514	E070	-14500
chr6	124545680	124545730	E074	8666
chr6	124511476	124511787	E081	-25227
chr6	124519820	124519896	E081	-17118
chr6	124520271	124520880	E081	-16134
chr6	124521275	124521397	E081	-15617
chr6	124521456	124521599	E081	-15415
chr6	124521796	124522255	E081	-14759
chr6	124522294	124522514	E081	-14500
chr6	124522653	124522828	E081	-14186
chr6	124538799	124538871	E081	1785
chr6	124539073	124539303	E081	2059
chr6	124545156	124545451	E081	8142
chr6	124576101	124577110	E081	39087
chr6	124577162	124577268	E081	40148
chr6	124511476	124511787	E082	-25227
chr6	124519820	124519896	E082	-17118
chr6	124520271	124520880	E082	-16134
chr6	124521275	124521397	E082	-15617
chr6	124521456	124521599	E082	-15415
chr6	124521796	124522255	E082	-14759
chr6	124522294	124522514	E082	-14500
chr6	124522653	124522828	E082	-14186
chr6	124544832	124545018	E082	7818
chr6	124545027	124545137	E082	8013
chr6	124545156	124545451	E082	8142
chr6	124545680	124545730	E082	8666
chr6	124576101	124577110	E082	39087

rs192590503