SNP Detail Info-rs1938407

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0341 (10232/29958,GnomAD)
G=0380 (11080/29118,TOPMED)
G=0290 (1450/5008,1000G)
G=0285 (1097/3854,ALSPAC)
G=0285 (1056/3708,TWINSUK)

Position: chr1:45256950 (GRCh38.p7) (1p34.1)

Phenotype: CD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 42 Enhancers around

Promoter: 10 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.45256950A>G
GRCh37.p13 chr 1	NC_000001.10:g.45722622A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.443	G=0.557
1000Genomes	American	Sub	694	A=0.790	G=0.210
1000Genomes	East Asian	Sub	1008	A=0.826	G=0.174
1000Genomes	Europe	Sub	1006	A=0.736	G=0.264
1000Genomes	Global	Study-wide	5008	A=0.710	G=0.290
1000Genomes	South Asian	Sub	978	A=0.870	G=0.130
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.715	G=0.285
The Genome Aggregation Database	African	Sub	8708	A=0.474	G=0.526
The Genome Aggregation Database	American	Sub	838	A=0.780	G=0.220
The Genome Aggregation Database	East Asian	Sub	1620	A=0.843	G=0.157
The Genome Aggregation Database	Europe	Sub	18490	A=0.721	G=0.278
The Genome Aggregation Database	Global	Study-wide	29958	A=0.658	G=0.341
The Genome Aggregation Database	Other	Sub	302	A=0.790	G=0.210
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.619	G=0.380
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.715	G=0.285

PMID	Title	Author	Journal
23958962	Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.	Gelernter J	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs1938407	0.0000149	cocaine dependence	23958962
rs1938407	0.000266	cocaine dependence	23958962

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	45740885	45741022	E067	18263
chr1	45763449	45763639	E067	40827
chr1	45763742	45763964	E067	41120
chr1	45740885	45741022	E068	18263
chr1	45763449	45763639	E068	40827
chr1	45763742	45763964	E068	41120
chr1	45764174	45764276	E068	41552
chr1	45764378	45764438	E068	41756
chr1	45765895	45766365	E068	43273
chr1	45766366	45766535	E068	43744
chr1	45763449	45763639	E069	40827
chr1	45763742	45763964	E069	41120
chr1	45673402	45673444	E070	-49178
chr1	45763449	45763639	E070	40827
chr1	45763742	45763964	E070	41120
chr1	45764174	45764276	E070	41552
chr1	45764378	45764438	E070	41756
chr1	45765503	45765553	E070	42881
chr1	45765742	45765796	E070	43120
chr1	45765895	45766365	E070	43273
chr1	45766366	45766535	E070	43744
chr1	45768432	45768528	E070	45810
chr1	45730990	45731184	E071	8368
chr1	45731694	45731816	E071	9072
chr1	45731853	45732394	E071	9231
chr1	45763449	45763639	E071	40827
chr1	45763742	45763964	E071	41120
chr1	45764174	45764276	E071	41552
chr1	45764378	45764438	E071	41756
chr1	45765895	45766365	E071	43273
chr1	45768432	45768528	E071	45810
chr1	45763449	45763639	E072	40827
chr1	45763742	45763964	E072	41120
chr1	45764174	45764276	E072	41552
chr1	45764378	45764438	E072	41756
chr1	45765895	45766365	E072	43273
chr1	45766366	45766535	E072	43744
chr1	45740885	45741022	E074	18263
chr1	45764174	45764276	E074	41552
chr1	45764378	45764438	E074	41756
chr1	45771138	45771178	E082	48516
chr1	45771540	45771632	E082	48918

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr1	45768819	45771112	E067	46197
chr1	45768819	45771112	E068	46197
chr1	45768819	45771112	E069	46197
chr1	45768819	45771112	E070	46197
chr1	45768819	45771112	E071	46197
chr1	45768819	45771112	E072	46197
chr1	45768819	45771112	E073	46197
chr1	45768819	45771112	E074	46197
chr1	45768819	45771112	E081	46197
chr1	45768819	45771112	E082	46197

rs1938407