SNP Detail Info-rs1974956

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

ZNF407 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0353 (10584/29916,GnomAD)
G==0437 (12745/29118,TOPMED)
G==0340 (1702/5008,1000G)
G==0299 (1151/3854,ALSPAC)
G==0280 (1037/3708,TWINSUK)

Position: chr18:74782885 (GRCh38.p7) (18q22.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 22 Enhancers around

Promoter: 0 Promoter around

Molecule type	Change	Amino acid[Codon]	SO Term
ZNF407 transcript variant 2	NM_001146189.1:c.	N/A	Intron Variant
ZNF407 transcript variant 3	NM_001146190.1:c.	N/A	Intron Variant
ZNF407 transcript variant 1	NM_017757.2:c.	N/A	Intron Variant
ZNF407 transcript variant X2	XM_005266726.4:c.	N/A	Intron Variant
ZNF407 transcript variant X2	XM_011526068.2:c.	N/A	Intron Variant
ZNF407 transcript variant X4	XM_011526069.2:c.	N/A	Intron Variant
ZNF407 transcript variant X5	XM_011526070.1:c.	N/A	Intron Variant
ZNF407 transcript variant X3	XM_017025838.1:c.	N/A	Intron Variant
ZNF407 transcript variant X6	XM_006722500.3:c.	N/A	Genic Downstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.673	A=0.327
1000Genomes	American	Sub	694	G=0.220	A=0.780
1000Genomes	East Asian	Sub	1008	G=0.052	A=0.948
1000Genomes	Europe	Sub	1006	G=0.290	A=0.710
1000Genomes	Global	Study-wide	5008	G=0.340	A=0.660
1000Genomes	South Asian	Sub	978	G=0.330	A=0.670
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.299	A=0.701
The Genome Aggregation Database	African	Sub	8700	G=0.619	A=0.381
The Genome Aggregation Database	American	Sub	836	G=0.170	A=0.830
The Genome Aggregation Database	East Asian	Sub	1620	G=0.055	A=0.945
The Genome Aggregation Database	Europe	Sub	18458	G=0.266	A=0.733
The Genome Aggregation Database	Global	Study-wide	29916	G=0.353	A=0.646
The Genome Aggregation Database	Other	Sub	302	G=0.170	A=0.830
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.437	A=0.562
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.280	A=0.720

PMID	Title	Author	Journal
24962325	Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.	Kapoor M	Drug Alcohol Depend

SNP ID	p-value	Traits	Study
rs1974956	9.72E-06	alcohol dependence (age at onset)	24962325

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr18	72509582	72509739	E068	14741
chr18	72508835	72509567	E069	13994
chr18	72509582	72509739	E069	14741
chr18	72492278	72492328	E070	-2513
chr18	72497750	72497820	E070	2909
chr18	72508439	72508756	E070	13598
chr18	72508835	72509567	E070	13994
chr18	72509582	72509739	E070	14741
chr18	72509820	72510344	E070	14979
chr18	72539571	72539621	E070	44730
chr18	72540180	72540243	E070	45339
chr18	72540297	72540398	E070	45456
chr18	72507643	72508030	E081	12802
chr18	72508315	72508373	E081	13474
chr18	72508439	72508756	E081	13598
chr18	72508835	72509567	E081	13994
chr18	72509582	72509739	E081	14741
chr18	72507643	72508030	E082	12802
chr18	72508315	72508373	E082	13474
chr18	72508439	72508756	E082	13598
chr18	72508835	72509567	E082	13994
chr18	72509582	72509739	E082	14741

rs1974956