rs2019089

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0346 (10347/29906,GnomAD)
A==0292 (8517/29118,TOPMED)
A==0399 (1999/5008,1000G)
A==0396 (1525/3854,ALSPAC)
A==0409 (1515/3708,TWINSUK)
chr17:54360132 (GRCh38.p7) (17q22)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.54360132A>G
GRCh37.p13 chr 17NC_000017.10:g.52437493A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.108G=0.892
1000GenomesAmericanSub694A=0.520G=0.480
1000GenomesEast AsianSub1008A=0.657G=0.343
1000GenomesEuropeSub1006A=0.405G=0.595
1000GenomesGlobalStudy-wide5008A=0.399G=0.601
1000GenomesSouth AsianSub978A=0.430G=0.570
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.396G=0.604
The Genome Aggregation DatabaseAfricanSub8712A=0.154G=0.846
The Genome Aggregation DatabaseAmericanSub834A=0.570G=0.430
The Genome Aggregation DatabaseEast AsianSub1612A=0.703G=0.297
The Genome Aggregation DatabaseEuropeSub18446A=0.394G=0.605
The Genome Aggregation DatabaseGlobalStudy-wide29906A=0.346G=0.654
The Genome Aggregation DatabaseOtherSub302A=0.390G=0.610
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.292G=0.707
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.409G=0.591
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs20190897.28E-05alcohol withdrawal symptoms22072270

eQTL of rs2019089 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2019089 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr175243990352440133E0702410
chr175248620452486462E08148711