rs2033831

Homo sapiens
A>G
KIAA0922 : 500B Downstream Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0196 (5885/29978,GnomAD)
A==0175 (5123/29118,TOPMED)
A==0181 (908/5008,1000G)
A==0204 (788/3854,ALSPAC)
A==0203 (753/3708,TWINSUK)
chr4:153637999 (GRCh38.p7) (4q31.3)
AD
GWASdb2
1   publication(s)
See rs on genome
38 Enhancers around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.153637999A>G
GRCh37.p13 chr 4NC_000004.11:g.154559151A>G

Gene: KIAA0922, KIAA0922(plus strand): 500B Downstream Variant

Molecule type Change Amino acid[Codon] SO Term
TMEM131L transcript variant 1NM_001131007.1:c.N/AN/A
TMEM131L transcript variant 2NM_015196.3:c.N/AN/A
TMEM131L transcript variant X1XM_011531780.1:c.N/ADownstream Transcript Variant
TMEM131L transcript variant X2XM_011531781.1:c.N/ADownstream Transcript Variant
TMEM131L transcript variant X7XM_011531783.1:c.N/ADownstream Transcript Variant
KIAA0922 transcript variant X3XM_017007924.1:c.N/ADownstream Transcript Variant
TMEM131L transcript variant X5XM_017007925.1:c.N/ADownstream Transcript Variant
TMEM131L transcript variant X6XM_017007926.1:c.N/ADownstream Transcript Variant
KIAA0922 transcript variant X7XM_017007927.1:c.N/ADownstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.151G=0.849
1000GenomesAmericanSub694A=0.200G=0.800
1000GenomesEast AsianSub1008A=0.214G=0.786
1000GenomesEuropeSub1006A=0.188G=0.812
1000GenomesGlobalStudy-wide5008A=0.181G=0.819
1000GenomesSouth AsianSub978A=0.170G=0.830
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.204G=0.796
The Genome Aggregation DatabaseAfricanSub8728A=0.146G=0.854
The Genome Aggregation DatabaseAmericanSub838A=0.210G=0.790
The Genome Aggregation DatabaseEast AsianSub1620A=0.229G=0.771
The Genome Aggregation DatabaseEuropeSub18490A=0.216G=0.783
The Genome Aggregation DatabaseGlobalStudy-wide29978A=0.196G=0.803
The Genome Aggregation DatabaseOtherSub302A=0.230G=0.770
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.175G=0.824
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.203G=0.797
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs20338318.73E-05alcohol dependence21314694

eQTL of rs2033831 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2033831 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4154544060154544220E067-14931
chr4154544235154544432E067-14719
chr4154556978154557047E068-2104
chr4154569418154569600E06810267
chr4154569641154569691E06810490
chr4154572279154572419E06813128
chr4154572457154572721E06813306
chr4154572812154573112E06813661
chr4154544060154544220E069-14931
chr4154544235154544432E069-14719
chr4154544485154544529E069-14622
chr4154544060154544220E071-14931
chr4154544235154544432E071-14719
chr4154544485154544529E071-14622
chr4154556978154557047E071-2104
chr4154572279154572419E07113128
chr4154572457154572721E07113306
chr4154572812154573112E07113661
chr4154576130154576392E07116979
chr4154577211154577426E07118060
chr4154577633154577887E07118482
chr4154577938154578139E07118787
chr4154544060154544220E072-14931
chr4154544235154544432E072-14719
chr4154544485154544529E072-14622
chr4154556978154557047E072-2104
chr4154572279154572419E07213128
chr4154572457154572721E07213306
chr4154572812154573112E07213661
chr4154544060154544220E074-14931
chr4154544235154544432E074-14719
chr4154544485154544529E074-14622
chr4154544768154544851E074-14300
chr4154556978154557047E074-2104
chr4154572279154572419E07413128
chr4154572457154572721E07413306
chr4154572812154573112E07413661
chr4154540379154540459E082-18692







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr4154605010154606530E06745859
chr4154605010154606530E06845859
chr4154605010154606530E06945859
chr4154607237154607290E07148086
chr4154605010154606530E07245859
chr4154605010154606530E07345859
chr4154605010154606530E07445859