rs2037955

Homo sapiens
C>A
NOD1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0223 (6692/29912,GnomAD)
A=0238 (6936/29118,TOPMED)
A=0281 (1407/5008,1000G)
A=0187 (719/3854,ALSPAC)
A=0196 (728/3708,TWINSUK)
chr7:30472333 (GRCh38.p7) (7p14.3)
AD
GWASdb2
1   publication(s)
See rs on genome
123 Enhancers around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.30472333C>A
GRCh37.p13 chr 7NC_000007.13:g.30511949C>A
NOD1 RefSeqGeneNG_013025.1:g.11445G>T

Gene: NOD1, nucleotide binding oligomerization domain containing 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
NOD1 transcriptNM_006092.2:c.N/AIntron Variant
NOD1 transcript variant X1XM_005249568.1:c.N/AIntron Variant
NOD1 transcript variant X6XM_005249572.1:c.N/AIntron Variant
NOD1 transcript variant X4XM_006715633.2:c.N/AIntron Variant
NOD1 transcript variant X2XM_011515079.1:c.N/AIntron Variant
NOD1 transcript variant X5XM_011515081.2:c.N/AIntron Variant
NOD1 transcript variant X7XM_011515083.1:c.N/AIntron Variant
NOD1 transcript variant X9XM_011515084.1:c.N/AIntron Variant
NOD1 transcript variant X10XM_011515085.1:c.N/AIntron Variant
NOD1 transcript variant X11XM_011515087.1:c.N/AIntron Variant
NOD1 transcript variant X14XM_011515088.2:c.N/AIntron Variant
NOD1 transcript variant X8XM_017011674.1:c.N/AIntron Variant
NOD1 transcript variant X10XM_017011675.1:c.N/AIntron Variant
NOD1 transcript variant X19XM_005249576.1:c.N/AGenic Upstream Transcript Variant
NOD1 transcript variant X3XM_011515080.2:c.N/AGenic Upstream Transcript Variant
NOD1 transcript variant X12XR_001744529.1:n.N/AIntron Variant
NOD1 transcript variant X17XR_001744530.1:n.N/AIntron Variant
NOD1 transcript variant X13XR_926908.2:n.N/AIntron Variant
NOD1 transcript variant X16XR_926909.2:n.N/AIntron Variant
NOD1 transcript variant X18XR_926910.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.670A=0.330
1000GenomesAmericanSub694C=0.830A=0.170
1000GenomesEast AsianSub1008C=0.615A=0.385
1000GenomesEuropeSub1006C=0.830A=0.170
1000GenomesGlobalStudy-wide5008C=0.719A=0.281
1000GenomesSouth AsianSub978C=0.700A=0.300
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.813A=0.187
The Genome Aggregation DatabaseAfricanSub8700C=0.692A=0.308
The Genome Aggregation DatabaseAmericanSub838C=0.840A=0.160
The Genome Aggregation DatabaseEast AsianSub1608C=0.675A=0.325
The Genome Aggregation DatabaseEuropeSub18464C=0.821A=0.178
The Genome Aggregation DatabaseGlobalStudy-wide29912C=0.776A=0.223
The Genome Aggregation DatabaseOtherSub302C=0.780A=0.220
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.761A=0.238
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.804A=0.196
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs20379550.000875alcohol dependence21314694

eQTL of rs2037955 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2037955 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr73046828130468744E067-43205
chr73046880130469039E067-42910
chr73046985930469935E067-42014
chr73046994530470229E067-41720
chr73047027030470789E067-41160
chr73050842330511183E067-766
chr73054261830543009E06730669
chr73046880130469039E068-42910
chr73046985930469935E068-42014
chr73046994530470229E068-41720
chr73047027030470789E068-41160
chr73047115730471292E068-40657
chr73047253230472582E068-39367
chr73050777730507889E068-4060
chr73050789530507976E068-3973
chr73050811930508201E068-3748
chr73050827430508351E068-3598
chr73050842330511183E068-766
chr73051120530511612E068-337
chr73051188230512052E0680
chr73054543530545502E06833486
chr73046828130468744E069-43205
chr73046880130469039E069-42910
chr73046985930469935E069-42014
chr73046994530470229E069-41720
chr73047027030470789E069-41160
chr73050349130504317E069-7632
chr73050440730504611E069-7338
chr73050524830505892E069-6057
chr73050590430506184E069-5765
chr73050842330511183E069-766
chr73054261830543009E06930669
chr73046815930468232E070-43717
chr73050842330511183E070-766
chr73046815930468232E071-43717
chr73046828130468744E071-43205
chr73046880130469039E071-42910
chr73046985930469935E071-42014
chr73046994530470229E071-41720
chr73047027030470789E071-41160
chr73047115730471292E071-40657
chr73047131730471367E071-40582
chr73047253230472582E071-39367
chr73047329530473443E071-38506
chr73047480730474925E071-37024
chr73047497330475043E071-36906
chr73050319130503464E071-8485
chr73050349130504317E071-7632
chr73050440730504611E071-7338
chr73050471630504847E071-7102
chr73050487930505041E071-6908
chr73050505730505242E071-6707
chr73050811930508201E071-3748
chr73050827430508351E071-3598
chr73050842330511183E071-766
chr73054261830543009E07130669
chr73046828130468744E072-43205
chr73046880130469039E072-42910
chr73046985930469935E072-42014
chr73046994530470229E072-41720
chr73047027030470789E072-41160
chr73047115730471292E072-40657
chr73050440730504611E072-7338
chr73050471630504847E072-7102
chr73050487930505041E072-6908
chr73050505730505242E072-6707
chr73050524830505892E072-6057
chr73050811930508201E072-3748
chr73050827430508351E072-3598
chr73050842330511183E072-766
chr73054165930541772E07229710
chr73054261830543009E07230669
chr73046880130469039E073-42910
chr73046985930469935E073-42014
chr73046994530470229E073-41720
chr73047027030470789E073-41160
chr73047115730471292E073-40657
chr73050777730507889E073-4060
chr73050789530507976E073-3973
chr73050811930508201E073-3748
chr73050827430508351E073-3598
chr73050842330511183E073-766
chr73051120530511612E073-337
chr73054261830543009E07330669
chr73046815930468232E074-43717
chr73046828130468744E074-43205
chr73046880130469039E074-42910
chr73046985930469935E074-42014
chr73046994530470229E074-41720
chr73047027030470789E074-41160
chr73047115730471292E074-40657
chr73047131730471367E074-40582
chr73047345330474547E074-37402
chr73047480730474925E074-37024
chr73047497330475043E074-36906
chr73050349130504317E074-7632
chr73050440730504611E074-7338
chr73050811930508201E074-3748
chr73050827430508351E074-3598
chr73050842330511183E074-766
chr73051585130516048E0743902
chr73051607030516264E0744121
chr73051632630516463E0744377
chr73051653030516629E0744581
chr73051669730516768E0744748
chr73051678430517094E0744835
chr73051733130517381E0745382
chr73047253230472582E081-39367
chr73048838330489124E081-22825
chr73048954130489644E081-22305
chr73050275330502894E081-9055
chr73050319130503464E081-8485
chr73054261830543009E08130669
chr73055291230552976E08140963
chr73055316530553219E08141216
chr73055355330553618E08141604
chr73055363530553743E08141686
chr73055388530554062E08141936
chr73055536230555864E08143413
chr73055604030556094E08144091
chr73055642930556493E08144480
chr73055664630556804E08144697
chr73055388530554062E08241936










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr73051741330519291E0675464
chr73054344630545143E06731497
chr73054514830545328E06733199
chr73051741330519291E0685464
chr73054344630545143E06831497
chr73054514830545328E06833199
chr73051741330519291E0695464
chr73054344630545143E06931497
chr73054514830545328E06933199
chr73051741330519291E0705464
chr73054344630545143E07031497
chr73054514830545328E07033199
chr73051741330519291E0715464
chr73054344630545143E07131497
chr73054514830545328E07133199
chr73051741330519291E0725464
chr73054344630545143E07231497
chr73054514830545328E07233199
chr73051741330519291E0735464
chr73054344630545143E07331497
chr73054514830545328E07333199
chr73051741330519291E0745464
chr73054344630545143E07431497
chr73054514830545328E07433199
chr73051741330519291E0815464
chr73054344630545143E08131497
chr73051741330519291E0825464
chr73054344630545143E08231497
chr73054514830545328E08233199