rs2061668

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
C==0409 (12224/29858,GnomAD)
C==0419 (12221/29118,TOPMED)
C==0312 (1564/5008,1000G)
A=0470 (1810/3854,ALSPAC)
C==0498 (1846/3708,TWINSUK)
chr3:147995192 (GRCh38.p7) (3q24)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.147995192C>A
GRCh37.p13 chr 3NC_000003.11:g.147712979C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.331A=0.669
1000GenomesAmericanSub694C=0.330A=0.670
1000GenomesEast AsianSub1008C=0.167A=0.833
1000GenomesEuropeSub1006C=0.419A=0.581
1000GenomesGlobalStudy-wide5008C=0.312A=0.688
1000GenomesSouth AsianSub978C=0.320A=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.530A=0.470
The Genome Aggregation DatabaseAfricanSub8686C=0.363A=0.637
The Genome Aggregation DatabaseAmericanSub832C=0.370A=0.630
The Genome Aggregation DatabaseEast AsianSub1606C=0.164A=0.836
The Genome Aggregation DatabaseEuropeSub18432C=0.453A=0.546
The Genome Aggregation DatabaseGlobalStudy-wide29858C=0.409A=0.590
The Genome Aggregation DatabaseOtherSub302C=0.490A=0.510
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.419A=0.580
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.498A=0.502
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs20616680.000016alcohol dependence(early age of onset)20201924
rs20616680.0000164alcoholismpha002892
rs20616680.0000339alcoholismpha002893
rs20616680.000034alcohol dependence20201924

eQTL of rs2061668 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2061668 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3147664853147664933E067-48046
chr3147679922147680133E067-32846
chr3147680311147680376E067-32603
chr3147680394147680486E067-32493
chr3147722292147722384E0679313
chr3147723440147723546E06810461
chr3147669197147669327E069-43652
chr3147679922147680133E069-32846
chr3147680311147680376E069-32603
chr3147680394147680486E069-32493
chr3147680691147680844E069-32135
chr3147664853147664933E071-48046
chr3147679922147680133E071-32846
chr3147680311147680376E071-32603
chr3147680394147680486E071-32493
chr3147680691147680844E071-32135
chr3147664853147664933E072-48046
chr3147664853147664933E074-48046
chr3147680691147680844E074-32135






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3147663698147664368E067-48611
chr3147663698147664368E068-48611
chr3147663698147664368E069-48611
chr3147663698147664368E071-48611
chr3147663698147664368E072-48611
chr3147663698147664368E073-48611
chr3147663698147664368E074-48611